Michael E Mitchell, MD

Associate Professor, Department of Surgery

Office Locations

8915 W. Connell Ave
Milwaukee, WI 53226
(414) 266-2491 (office)


Thoracic and Cardiac Surgery, Congenital Cardiac Surgery
Areas of Interest
  • Cardiovascular surgery
  • Neonatal and infant cardiac surgery
  • Heart, lung and heart/lung transplantation
  • Valve reconstruction
  • Tracheal suspension
  • Adult congenital cardiac surgery

Education & Awards

  • 2003, Children's Hospital Boston, Chief Resident
  • 1995, Harvard Medical School (Boston, MA), MD
  • 2001, Brigham & Women's Hospital
  • 2002, Brigham & Women's Hospital
  • 2004, The Children's Hospital of Philadelphia
  • 2013 Milwaukee’s Top Doctors. Milwaukee Magazine
  • 2013-2018 NIH/NHLBI R01 funding ($3.4M)

National elected/appointed leadership and committee positions

  • 2007-Present National Institutes of Health Pediatric Mechanical Support Device Committee
  • 2010-Present United Network for Organ Sharing, Region 7 Regional Heart Review Board Member
  • 4/1/12-4/1/13 American College of Cardiology ACC13 Annual Scientific Session Program Committee
  • 2012-Present American Heart Association, Cardiovascular Development CL Reviewer
  • 2012-Present Congenital Heart Surgeon’s Society, Ethics Committee
  • 4/1/13-4/1/14 American College of Cardiology ACC14 Annual Scientific Session Program Committee
  • 4/1/13-Present American College of Cardiology, Chairperson, Congenital Program Committee

Research & Publications

  • Fetal and neonatal cardiac surgery
  • Genetics of congenital heart disease
  • Pediatric cardiac surgery
  • Prenatal and neonatal diagnosis and outcomes
  • Pediatric tracheal surgery
  • Heart transplant – Noninvasive detection of rejection


  • Mitchell ME, Litwin SB, Tweddell JS. Complex Atrioventricular Canal. Semin Thoracic Cardiovasc Surg Pediatr Card Surg Annu. 2007:32-41.
  • Mitchell ME, Sander TL, Klinker DB, Tomita-Mitchell, A. The Molecular Basis of Congenital Heart Disease. Semin Thorac Cardiovasc Surg. 2007 Fall;19(3):228-37.
  • Draus JM, Hauck MA, Austin EH III, Goetsch M, Tomita-Mitchell A, Mitchell ME. Investigation of Somatic NKX2-5 Mutations in Congenital Heart Disease. J Med Genet. 2009 Feb;45(2)115-22.
  • Mitchell ME, McManus M, Dietz J, Camitta BM, Szabo S, Havens P, Absidia Corymbifera Endocarditis: Survival from Disseminated Mucormycosis (Zygomycosis) with Radical Resection of Tricuspid Valve and Right Ventricular Free Wall. J Thorac Cardiovasc Surg 2010 Apr;139(4):e71-2.
  • Tomita-Mitchell A, Mahnke DK, Larson JM, Ghanta S, Feng Y, Simpson PM, Broeckel U, Duffy K, Tweddell JS, Grossman WJ, Routes JM, Mitchell ME. Multiplexed Quantitative Real-time PCR to Detect 22q11.2 Deletion in Patients with Congenital Heart Disease. Physiol Genomics. 2010 Sep;42A(1):52-60. Epub 2010 Jun 15.
  • Mitchell ME. Anterior Tracheal Suspension. Operative Techniques in Thoracic and Cardiovascular Surgery. 2011 Winter 16(4);331-339.
  • Mitchell ME, Barnes ME, Tweddell JS. Pulmonary Atresia with Intact Ventricular Septum. In, Cardiothoracic Surgery Review. Kenneth L. Franco & Vinod H. Thourani, editors. Lippincott, Williams & Wilkins. December 16, 2011.
  • Tomita-Mitchell A, Mahnke DK, Struble CA, Tuffnell ME, Stamm KD, Hidestrand M, Harris SE, Goetsch MA, Simpson PM, Bick DP, Broeckel U, Pelech AN, Tweddell JS, Mitchell ME. Human Gene Copy Number Spectra Analysis in Congenital Heart Malformations. Physiol Genomics. 2012 May 1;44(9):518-41. Epub 2012 Feb 7.
  • Lamers LJ, Frommelt PC, Mussatto KA, Jaquiss RD, Mitchell ME, Tweddell JS. Coarctectomy combined with an interdigitating arch reconstruction results in a lower incidence of recurrent arch obstruction after the Norwood procedure than coarctectomy alone. J Thorac Cardiovasc Surg. 2012 May;143(5):1098-102. Epub 2011 Nov 3.
  • Tweddell, JS, Earing MG, Bartz PJ, Dunham-Ingles JL, Woods RK, Mitchell ME. Valve-Sparing Aortic Root Reconstruction in Children, Teenagers, and Young Adults. Ann Thorac Surg. 2012 Aug;94(2):587-91. Epub 2012 Jun 28.
  • James S. Tweddell, Michael E. Mitchell, Ronald K. Woods and James A. Quintessenza. Construction of the Right Ventricle-to-Pulmonary Artery Conduit in the Norwood: The “Dunk” Technique. Operative Techniques in Thoracic and Cardiovascular Surgery. Accepted.
  • Hidestrand M, Tomita-Mitchell A, Hidestrand PM, Oliphant A, Goetsch M, Stamm K, Liang H-L, Castleberry C, Benson DW, Stendahl G, Simpson PM, Berger S, Tweddell JS, Zangwill S, Mitchell ME. Highly Sensitive Non-Invasive Cardiac Transplant Rejection Monitoring Using Targeted Quantification of Donor Specific Cell Free DNA. J Am Coll Cardiol 2013 Oct 4. pii: S0735-1097(13)05537-X. doi: 10.1016/j.jacc.2013.09.029. Epub 2013 Aug 2.