Clinical trials in cancer and blood disorders

Through research, our team is able to offer more options to patients and families in their battle with cancer and blood disorders. Offering treatment options is our commitment to helping patients and families achieve the best possible outcomes.

Clinical trials help us understand and test new ways to diagnose and treat cancer and blood disorders, resulting in higher survival rates, and reducing short-term and long-term side effects of therapy. New and improved treatment options then are available to help patients worldwide.

Many types of clinical trials available

We offer a broad range of clinical trials, from phase I and other early phase clinical trials, through phase III trials. Phase I trials are for patients whose disease can’t be effectively treated using regular treatments. Phase III studies typically are considered standard care and involve evaluating a series of small changes to regular treatment.

Access to new, cutting-edge treatments

Children’s participates in several groups of top hospitals nationwide and around the world that work together to develop and study new therapies.

We are part of Children’s Oncology Group (COG), the world’s largest organization devoted entirely to pediatric cancer research. As a COG Phase 1 Center, an elite distinction awarded to fewer than 25 sites in the nation, Children’s Hospital is able to offer patients and families access to new, cutting-edge treatments. That includes studies led by our own researchers and multicenter clinical trials initiated by our partners at leading programs around the country.

Participating in a clinical trial could mean testing the effectiveness of a new therapy or simply donating tissue so that researchers can better understand the underlying parts of these diseases. The safety of our patients always comes first, and Children’s Institutional Review Board carefully reviews each project before it is approved. Although participation in clinical trials is voluntary, many of our patients’ families take the opportunity to help us advance cancer and blood disorders research and possibly help future generations of children.

Recent clinical trials

Some of our clinical trials have included:

  • Photodynamic therapy for brain tumors
  • Combination chemotherapy, radiation therapy, and/or surgery in treating patients with high-risk kidney tumors 
  • Biomarkers in tumor tissue samples from patients with newly diagnosed neuroblastoma or ganglioneuroblastoma
  • Radiation biodosimetry in children undergoing total body irradiation
  • Combination chemotherapy in treating young patients with Down syndrome and acute myeloid leukemia or myelodysplastic syndromes
  • Pharmacokinetics of liquid hydroxyurea in pediatric patients with sickle cell anemia

Participate in a clinical trial

Want to get involved? Find a list of all the current studies available from Children’s Research Institute or learn more about research at Children’s Hospital: