Ramani Ramchandran, PhD
 Titles
Investigator, Children's Research Institute; associate professor, Pediatrics and Cell Biology, Neurobiology and Anatomy, director, Developmental Vascular Biology program and Zebrafish Drug Screening Core, The Medical College of Wisconsin.
Division
Pediatrics
Research center/program
Developmental Vascular Biology Program
Research interests
Cell and developmental biology
Study interests
Angioblast development in vertebrates, role of axon guidance genes in vascular development, translational disease models in fish.
Education
Doctorate, Medical College of Georgia, Augusta, 1997; post-doctoral fellowship, Harvard Medical School, Boston, 1997-2002.
Honors
Batliboi Scholarship Award (bachelor's degree), 1990; Batliboi Scholarship Award (master's degree), 1991; Tata Memorial Scholarship Award, 1992; Graduate Research Assistantship Award, 1992; Third place, Sigma XI, 1997; Listed in "Who's Who Among Students in American Universities and Colleges," 1997; Special Recognition Award from Student Government Association, 1997; Ruth L. Kirchstein National Research Service Award, 2001; National Cancer Institute Scholar Award, 2002; Nominated for Outstanding Mentor Award, NCI, National Institutes of Health, 2004; Listed in Madison, Wis., "Who's Who of Business Leaders and Professionals," 2006; Cash Performance Award, NIH, 2006; Two Year Complimentary Membership to American Association of Anatomist (successful nomination of a Bensley Award Recipient), 2007; The Donald & Judith Alstadt Charitable Research Foundation Award, 2010.
Representative publications
- Makky K, Duvnjak P, Pramanik K, Ramchandran R and Mayer AN. A Whole-Animal Microplate Assay for Metabolic Rate Using Zebrafish. Journal of Bio Molecular Screening. 2008 Dec. 13; (10):960-967. PMID:19029015.
- Jia Y, Wu S-L, Isenberg JS, Sipes JM, Field L, Zeng B, Bandle RW, Ramchandran R, Karger BL, and Roberts DD. Thiolutin Inhibits Endothelial Cell Adhesion by Perturbing Hsp27 Interactions with the Actin Cytoskeleton. Cell Stress and Chaperones. 2010 Mar.15; (2):165-181; PMC2866983.
- Kanungo J, Zhen Y, Amin N, Kaur S, Ramchandran R, and Pant H. Specific Inhibition of Cyclin-dependent Kinase 5 Activity Induces Motor Neuron Development in Vivo 2009. Biochemical and Biophysical Research Communications 386. 2009; 263-267; PMC2758157.
- Li K, Blum Y, Verma A, Liu Z, Pramanik K, Leigh N, Chun C, Samant G, Zhao B, Garnaas M, Horswill M, Stanhope S, North P, Miao R, Wilkinson G, Affolter M, and Ramchandran R. A Noncoding Antisense RNA at the Tie-1 Locus Regulates Tie-1 Transcript Levels and Function in vivo. Blood. 2010 Jan. 7; 115(1):133-9; PMC2803688.
- Verma A, Bhattacharya R, Remadevi I, Li K, Pramanik K, Samant G, Horswill M, Chun C, Mukhopadhyay D, Ramchandran R, and Wilkinson G. Ecscr Promotes Angioblast Migration during Vasculogenesis and Enchances kdr Sensitivity. Blood. 2010, Jun. 3;115(22):4614-22; PMC2881497. **Inside Blood commentary on EC-specific Chemotaxis Receptor: a Double-edged Sword, p. 4614.
- Zhao B, Chun C, Liu Z, Horswill M, Pramanik K, Wilkinson G, Ramchandran R. and Miao R. Nogo-B Receptor is Essential for Angiogenesis in Vivo via AKT Pathway. Blood. 2010. Sep. 2; [Epub ahead of print]. PMID: 20813898.
Grants
1R01HL090712-01A2 (Ramchandran, R.) 2009-2014 - NIH/NHLBI. Roundabout4 signaling in endothelial cells. Role: PI
3R01HL090712-01A2S1 (Ramchandran, R.) 2009-2011 - NIH/NHLBI. Administrative supplement for Roundabout4 signaling in endothelial cells. Role: PI
1R43NS067749-01 (Ferrante, A and Ramchandran, R) 2010-2012 High content discovery assay for muscular dystrophy therapeutics - Role: Co-I
HL007792 (Harder, D) 2009-2014 NIH T32 Training Program - Hypertension and Vascular Biology Training Grant
1R43HL097465-01 (Ferrante, A. and Ramchandran, R.) 2009-2010 - NIH/NHLBI. Fully automated angiogenesis drug discovery assay in zebrafish- Role Co-I
HL007792 (Harder, D) 2009-2014 - NIH T32 Training Program. Hypertension and Vascular Biology Training Grant Role: Mentor
10POST4180008 (Li, Keguo - member of Ramchandran Lab) 2010-2012 - American Heart Association Mid-West Affiliate Post-Doctoral Fellowship. Natural antisense transcript-mediated gene regulation in zebrafish vasculature.
10SDG4120011 (Samant, Ganesh - member of Ramchandran Lab) 2009-2011 - American Heart Association Mid-West Affiliate Post-Doctoral Fellowship. Identification of the physiologically relevant ligand for the angiogenic Roundabout-4 (Robo4) receptor.
(Ramchandran, R.) 2011 - Marjorie Siebert Aylen Foundation. MYCN Zebrafish Model for Neuroblastoma- Role: PI
(Ramchandran, R.) 2011 - Alvin and Marion Birnschein Foundation . MYCN Zebrafish Model for Neuroblastoma- Role: PI
(Ramchandran, R.) 2011 - The Donald & Judith Alstadt Charitable Research Foundation- Role: PI
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