Ulrich Broeckel, MD

Titles
Associate director, Children's Research Institute; associate professor, Medicine (Cardiology), adjunct associate professor, Physiology and Pediatrics, Medical College of Wisconsin.

Division
Genomic Pediatrics

Research center/program
Cardiothoracic Surgery, Individualized Medicine Institute

Research interests
Genetic diseases/genomics, heart disease

Study interests
Coronary artery disease, left ventricular hypertrophy, identification of genes underlying polygenic cardiovascular disease, renal failure.

Education
Medical degree, University of Heidelberg, Germany, 1994; Cardiology and Nephrology internship and residency, University of Regensburg, Germany, 1996; postdoctoral fellow, Physiology, Medical College of Wisconsin, Milwaukee, 2000.

Honors
Young Investigator Award, 2000. 

Representative publications 

• Kugathasan S, Collins N, Maresso K, Hoffmann RG, Stephens M, Werli SK, Rudolph C, Broeckle U. CARD 15 Gene Mutations and Risk for Early Surgery in Pediatric-Onset Crohn's Disease. Clinical Gastroenterology and Hepatology. 2004 Nov.; 2(11):1003-9.
• Fischer M, Broeckel U, Holmer S, Baessler A, Hengstenberg C, Mayer B, Erdmann J, Klein G, Riegger G, Jacob HJ, Schunkert H. Distinct Heritable Patterns of Angiographic Coronary Artery Diseases in Families with Myocardial Infarction. Circulation. 2005 Feb. 22; 111(7):855-62.
• Hamet P, Merlo E, Seda O, Broeckel U, Tremblay J, Kaldunski M, Gaudet D, Bouchard G, Deslauriers B, Gagnon F, Anroniol G, Kotchen TA, Pausova Z, Labuda M, Jomphe M, Gossard F, Kirova R, Tonellato P, Orlov SN, Pintos J, Platko J, Judson TJ, Rioux D, Lander ES, Cowley AW. Quantitative Founder Effect Analysis of French-Canadian Families Identifies Specific Loci Contributing to Metabolic Phenotypes of Hypertension. The American Journal of Human Genetics. 2005 May; 76(5):815-32.
• Kugathasan S, Loizides A, Babusukumar U, McGuire E, Wang T, Hooper P, Nebel J, Kofman G, Noel R, Broeckel U, Tolia V. Comparative Phenotypic and CARD15 Mutational Analysis among African American, Hispanic and White Children with Crohn's Disease. Inflammatory Bowel Diseases. 2005 July; 11(7):631-8.
• Maloney JP, Broeckel U. Epidemiology, Risk Factors and Genetics of High Altitude-Related Pulmonary Disease. Clinics in Chest Medicine. 2005 Sep.; 26(3):395-404.

Grants

• R01, National Institutes of Health/NHLB1, Genetics of CRP in Families with Myocardial Infarction to Identify Genetic Variation in Candidate Genes within Regions we have Identified for CRP which are Functionally Related to Inflammation and Inflammatory Processes, principal investigator, 7/1/03-6/30/08.
• R01, National Institutes of Health/NHLB1, Genes of Hypertension in African Americans: Determining the Genes involved in Hypertension in African Americans, co-investigator, 8/1/03-7/31/07.
• National Institutes of Health/NCRR, General Clinical Research Center, Providing Informatics Infrastructure to Assist Investigators with Clinical Research Projects, Bioinformatics Core principal investigator, 12/1/91-11/30/06.
• Medical College of Wisconsin Cancer Center, Epidemiology and Genetics of Female Breast Cancer: Identifing New Genes that may Explain the Link between Breast Cancer, Obesity and how a Woman's Body uses Energy, principal investigator, 11/1/04-10/31/06.
• American Heart Association: Greater Midwest Affilate Pre-doctoral Award, Genetics of Hypertension in French Canadians: Evaluating for Genetic Involvement in Hypertension of the Chicoutimi-Saguenay-Lac-St. Jean Founder Population, sponsor, 1/1/05-12/31/06.

Contact
Children's Research Institute
8701 Watertown Plank Road
Wauwatosa, WI 53226
Phone: (414) 456-4409
E-mail: broeckel@mcw.edu