Qing (Robert) Miao, PhD

Investigator, Children's Research Institute
Associate professor, Pediatrics (Surgery and Pathology), the Medical College of Wisconsin

Office Locations

8701 Watertown Plank Rd.
Milwaukee, WI 53226
(414) 955-5701
(414) 955-6473 (fax)

Overview

Division

  • Pathology
  • Surgery

Research interests

  • Birthmarks and vascular anomalies
  • Cancer
  • Cell and developmental biology
  • Disease pathology

Education

  • Doctorate, Medical University of South Carolina, Charleston, 1997-2002
  • Postdoctoral fellowship, Yale University School of Medicine, New Haven, Conn.; 2002-2006

Education & Awards

Awards
  • ATVB Conference Merit Award for Young Investigators, American Heart Association's Council on Arteriosclerosis, Thrombosis and Vascular Biology, 2006
  • Scientist Development Awards, American Heart Association National Program, 2007
  • ATVB Conference Merit Award for Young Investigators, American Heart Association's Council on Arteriosclerosis, Thrombosis and Vascular Biology, 2010
  • Young Investigator Award, 5th Mayo Clinic Angiogenesis Symposium, 2012

Research & Publications

Research
  • Role of NgBR, National Institutes of Health, National Heart, Lung and Blood Institute, principal investigator
  • Nogo-B Receptor Modulates Sensitivity of Breast Cancer Cells to Chemotherapy and Radiation Therapy, State of Wisconsin Tax Check-off Program for Breast & Prostate Cancer Research, principal investigator
  • Roles of Nogo-B and Nogo-B Receptor (NgBR) in Tumor and Angiogenesis, American Cancer Society Pilot Research Grant, MCW Cancer Center, principal investigator
  • Role of NgBR in endothelial cell function and angiogenesis Source: NIH/NHLBI, R01HL108938, principal investigator, 9/1/2011 - 7/31/2016
  • Roles of NgBR in breast cancer initiation and progression Source: Wisconsin Breast Cancer Showhouse, principle investigator, 6/1/2013 - 5/30/2014
Representative publications

  • L. Acevedo, J. Yu, H. Erdjument-Bromage, R.Q. Miao, J.E. Kim, D. Fulton, P. Tempst, S.M. Strittmatter, W.C. Sessa. A new role for Nogo as a regulator of vascular remodeling. Nature Medicine. 10:382-388 (2004). PMID: 15034570
  • R.Q. Miao, Y. Gao, K.D. Harrison, J. Prendergast, L.M. Acevedo, J. Yu, F. Hu, S.M. Strittmatter, W.C. Sessa. Identification of a receptor necessary for Nogo-B stimulated chemotaxis of endothelial cells. Proceedings of the National Academy of Sciences of the United States of America. 103: 10997-11002 (2006). PMID: 16835300
  • K.D. Harrison, R.Q. Miao, C. Fernandez-Hernándo, Y. Suárez, A. Dávalos, W.C. Sessa. Nogo-B receptor stabilizes Niemann-Pick type C2 protein and regulates intracellular cholesterol trafficking. Cell Metabolism. 10(3): 208-18. (2009). PMID: 19723497
  • B. Zhao, C.Z. Chun, Z. Liu, M.A. Horswill, K. Pramanik, G.A. Wilkinson, R. Ramchandran, R.Q. Miao*. Nogo-B receptor is essential for in vivo angiogenesis in zebrafish via Akt pathway. Blood, 116(24) 5423-5433. (2010). * Corresponding author. PMID: 20813898
  • B. Wang, B. Zhao, P. North, A. Kong, J. Huang, R.Q. Miao*. Expression of NgBR is highly associated with estrogen receptor alpha and survivin in breast cancer. PloS One. 8(11):e78083. 2013. * Corresponding author. PMID:24223763