John E. Baker, PhD

Investigator, Children's Hospital of Wisconsin's Research Institute
Professor, Cardiothoracic Surgery, Pharmacology & Toxicology, and Biochemistry, Medical College of Wisconsin

Office Locations

Medical College of Wisconsin
8701 Watertown Plank Rd
Milwaukee, WI 53201
(414) 456-8706
(414) 453-9700


Dr. Baker is a researcher in the cardiovascular biology program in the Children's Research Institute. His study interests include ischemia, hypoxia, heart, molecular genetics, heart surgery and congenital heart defects, radiation injury to the cardiovascular system.

Education & Awards

  • 1986, Medical College of Wisconsin, Post Doctoral Fellowship
  • 1984, St. Thomas Hospital Medical School, London, Doctorate

Research & Publications

  • National Institutes of Health, Chronic Hypoxia and Resistance to Myocardial Ischemia, principal investigator
  • National Institutes of Health, Pharmacological Treatment for Radiation Injury. Allergy and Infectious Diseases, principal investigator
  • National Institutes of Health, Radiation Injury to the Heart, Allergy and Infectious Diseases, principal investigator

Recent representative publications

  • Safety and blood sample volume and quality of a refined retro-orbital bleeding technique in rats using a lateral approach.Sharma A, Fish BL, Moulder JE, Medhora M, Baker JE, Mader M, Cohen EP. 2014 Jan 22.
  • Cardiac injury after 10 gy total body irradiation: indirect role of effects on abdominal organs. Lenarczyk M, Lam V, Jensen E, Fish BL, Su J, Koprowski S, Komorowski RA, Harmann L, Migrino RQ, Li XA, Hopewell JW, Moulder JE, Baker JE. 2013 Sep
  • Heparin oligosaccharides inhibit chemokine (CXC motif) ligand 12 (CXCL12) cardioprotection by binding orthogonal to the dimerization interface, promoting oligomerization, and competing with the chemokine (CXC motif) receptor 4 (CXCR4) N terminus. Ziarek JJ, Veldkamp CT, Zhang F, Murray NJ, Kartz GA, Liang X, Su J, Baker JE, Linhardt RJ, Volkman BF. 2013 Jan 4
  • Intestinal microbiota as novel biomarkers of prior radiation exposure. Lam V, Moulder JE, Salzman NH, Dubinsky EA, Andersen GL, Baker JE. 2012 May
  • Intestinal microbiota determine severity of myocardial infarction in rats. Lam V, Su J, Koprowski S, Hsu A, Tweddell JS, Rafiee P, Gross GJ, Salzman NH, Baker JE. 2012 Apr

See all publications by Dr. Baker