Preimplantation Genetic Diagnosis (PGD) Program

What is preimplantation genetic diagnosis (PGD)?

Preimplantation genetic diagnosis (PGD) is a form of genetic testing used with in vitro fertilization. Your physician may recommend PGD if there is a chance that your embryos will be affected by certain chromosomal problems or genetic conditions.

Who may benefit from PGD:

  • Couples at increased risk for a child with a chromosomal problem, such as couples where the mother is older than 35.
  • Couples at increased risk to have a child with a genetic condition due to a family history of a genetic condition or an increased chance of a genetic condition based on ethnic background.
  • Couples who would like to increase the chance of having child with a certain HLA type (see below).

The PGD procedure allows genetic testing to be performed on early embryos before they are transferred into the uterus. This decreases the likelihood of a chromosomal abnormality or a genetic condition in your child.

PGD to find a bone marrow match

PGD also can help couples whose biological child is in need of a human leukocyte antigen (HLA)-matched hematopoietic progenitor cell (HPC) transplant, also called a bone marrow transplant. By using IVF and PGD, couples can identify and transfer an embryo that is an HLA match for the child in need of HPC transplant.

Find out more information about Fertility and Reproductive Medicine.

Learn more about the benefits of PGD.