Manu Sood, MD

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Specialties

  • Gastroenterology.
  • Pediatrics.

Board Certification(s)

  • Pediatric Gastroenterology.
  • Pediatrics.

Education

Medical School: Indira Gandhi Medical College, Shimla, India.
Pediatric Residency: Birmingham Children's Hospital, UK.
Gastroenterology and Hepatology Fellowship: Birmingham Children's Hospital, UK.
Clinical Research Training: University of Manchester, UK (Clinical Research in Cystic Fibrosis and Nutrition).
Post Fellowship Training: Motility and Functional GI Disorders, Children's Hospital of Orange County, CA, USA.

Faculty research

  • Principal Investigator: Effect of age and gender on activation of brain regions associated with visceral pain in children with irritable bowel syndrome and healthy controls.
  • Principal Investigator: Development of a tool to assess health related quality of life in children with constipation and fecal incontinence, Takeda Pharmaceutical Inc.
  • Principal Investigator: Capsaicin-sensitive transient receptor potential vanilloid one (TRPV1) and tyrosine kinase (TrkA) receptor expression in children with retrosternal pain. Children's Research Institute, Milwaukee.
  • Co-investigator: Polymeric diet for maintenance of disease remission in CrohnÕs Disease, SHS International, U.K.

Fellowship research

  • Principal Investigator: Study of bone density in children with cystic fibrosis and Effect of nutritional status, disease severity, and exercise on bone density, National Osteoporosis Society, UK.
  • Principal Investigator: Overnight feeding in children with cystic fibrosis and pancreatic enzymes. Cystic Fibrosis Trust, U.K.
  • Pprotein identification, and gel retardation assays to examine specific DNA-protein interactions. Experience with DNA footprinting techniques was also obtained.

Invited lectures/Workshops/Presentations/Site visits

International

  • Manu Sood, Gastric and small bowel motility disorders. Gastrointestinal Motility Symposium, New Delhi, India Oct, 2006.
  • Manu Sood, Aerophagia, 4th European Pediatric Gastrointestinal Motility Conference, London 2007.
  • Colin Rudolph, Manu Sood, High resolution esophageal manometry and simultaneous fluoroscopy-Live Demonstration, 4th European Pediatric Gastrointestinal Motility Conference, London 2007.
  • Manu Sood, Defecation Disorders Ð The Ins And The Outs. World Congress of Pediatric Gastroenterology, Hepatology and Nutrition, Brazil, 2008.
  • Manu Sood, Evaluation of Bowel Sensory Function. Neurogastroenterology and Motility - Joint International Neurogastroenterology and Motility Meeting, Chicago, 2009.
  • Manu Sood, Overview of Pediatric Motility GI Disorders- Investigation and Management, 24th Winter Meeting, British Society of Pediatric Gastroenterology, Hepatology and Nutrition Annual Meeting, Liverpool, 2010.

National

  • Manu Sood, Gastrointestinal tract and cystic fibrosis. United Kingdom Cystic Fibrosis Dieticians' Interest Group Meeting, Birmingham, U.K. 1999. 
  • Manu Sood, Metabolic bone disease in cystic fibrosis. United Kingdom Cystic Fibrosis Dieticians' Interest Group Meeting, London, U.K. 2001.
  • Manu Sood, Functional gastrointestinal disorders, Manchester Paediatric Gastroenterology Course, U.K. 2001.
  • Manu Sood, Colon Motility. First Adult and Paediatric Motility Interest Group Meeting, London, U.K. 2002.
  • Manu Sood, Cystic Fibrosis Liver Disease. British Society of Pediatric Gastroenterology, Hepatology and Nutrition -Allied Members Meeting, Leicester, U.K. 2003.
  • Manu Sood, Gastroesophageal Reflux, National Dysphagia Course, Manchester, U.K. 2004.
  • Manu Sood, Gastroesophageal Reflux, Esophageal Atresia and Gastroesophageal Reflux Symposium. Phoenix. July 2005.
  • Manu Sood, Evaluation and management of common problems following fundoplication. American Society of Parenteral and Enteral Nutrition, Dallas, 2006.
  • Manu Sood, Chronic Intestinal Pseudo-obstruction, Association of Pediatric Gastroenterology and Nutrition Nurses Meeting, Salt Lake City, 2007.
  • Manu Sood and Rina Sanghavi, Refractory Constipation-Where does it stop, Meet the Professor Breakfast, North American Society of Pediatric Gastroenterology, Hepatology and Nutrition, Salt Lake City, 2007. 
  • Manu Sood, Chronic Intestinal Pseudo-obstruction. American Society for Parenteral and Enteral Nutrition Annual Meeting, Chicago, 2008.
  • Manu Sood, Feeding intolerance and bowel motility in neonates. Neonatology Course, Minneapolis 2008.
  • Manu Sood Chronic intractable constipation Ð Meet the Professor Lunch, North American Society of Paediatric Gastroenterology, Hepatology and Nutrition, San Diego, 2008.
  • Manu Sood, Meet the Professor Breakfast. Digestive Disease Week, New Orleans 2010.
  • Sam Nurko, Manu Sood, Carlo Di Lorenzo, and others. Workshop on Anorectal Manometry, North American Society of Pediatric Gastroenterology, Hepatology and Nutrition, New Orleans 2010.

Regional

  • Manu Sood, Bone density and cystic fibrosis. Northern U.K. Cystic Fibrosis Meeting, Nantwich, U.K. 1997.
  • Manu Sood, Colon Motility in Children, Royal London Hospital, London, U.K. 2001.
  • Manu Sood, Gastroesophageal Reflux in Infants, Neonatal Nurses Regional Meeting. Southport, U.K. 2002.
  • Manu Sood, Gastroesophageal Reflux. National Dysphagia Course, Manchester, U.K. 2002. 
  • Manu Sood, Chronic Constipation. Manchester Paediatric Gastroenterology Course, U.K. 2002.
  • Manu Sood, Role of manometry in the diagnoses of achalasia. Transpenine Gastroenterology Meeting. Manchester, U.K. 2003.

Refereed journal publications/Original papers

  • Hung JC, Howie AF, Beckett GJ, Sood M, Hambleton G, Super M. The use of glutathione S-transferase A1 in the detection of cystic fibrosis liver disease. Journal of Paediatric and Child Health 1998;34(4)335-8.
  • Sood M, Murphy S. Chloacogenic polyp. J Pediatr Gastroenterol Nutr. 1998;27:523 & 529.
  • BuLock F, Sood M, Giovanni J, Green S. Left ventricular diastolic function in congenital myotonic dystrophy. Arch Dis Child 1999;80:267-270.
  • Sood M, Clarke J, Murphy MS. Covert biting of the buccal mucosa masquerading as haematemesis or haemoptysis in children. Acta Paediatr 1999;88:138-140.
  • Sood M, John P, Booth IW. Extensive low-flow venous malformations of the rectum and distal colon. J Pediatr Gastroenterol Nutr.2000;31;326, 330.
  • Sood M, Hambleton G, Super M, Adams J, Mughal M. Bone density in children with cystic fibrosis Arch Dis Child 2001;84:516-520.
  • Villarreal J, Sood M, Zangen T, Flores A, Michel R, Reddy N, DiLorenzo C, Hyman PE. Colonic Diversion for intractable constipation in children: colonic manometry guides clinical decision. J Pediatr Gastroenterol Nutr. 2001;33:588-591.
  • Murphy MS, Sood M, Johnson T. Use of lactose H2 breath test to monitor mucosal healing in coeliac disease. Acta Paediatr 2002;91:141-44.
  • Hyman PE, Bursch B, Sood M, Schwankovsky L, Cocjin J, Zeltzer L. Visceral pain associated disability syndrome: A descriptive analysis. J Pediatr Gastroenterol Nutr. 2002;35:663-8.
  • Sood M, Schwankovsky L M, Rowhani A, Ziring D, Furtado T, Hyman P E. Water load test in Children. J Pediatr Gastroenterol Nutr. 2002;35:199-201.
  • Sood M, Di Lorenzo C, Cocjin J, Flores A, Reddy N, Hyman PE. Ileal manometry in children. Neurogastroenterology and Motility. 2002;14:643-6.
  • Sood M, Hambleton G, Super M, Adams J, Mughal Z. Lean Body Mass in children with Cystic Fibrosis. Arch Dis Child. 2003;88(9):836.
  • Sood M, Joshi S, Mitchell J, Akobeng A, Thomas A. Growth in Children with H. pylori Infection and Dyspepsia. Arch Dis Child. 2005;90:1025-29.
  • Wynn RF, Sood M, Theilgaard-Moench K, Jones CJ, Gombart AF, Gharib M, Koeffler P, Borregaard N, Arkwright PD. Intractable diarrhoea of infancy caused by neutrophil specific granule deficiency and cured by stem cell transplantation. Gut. 2006:55;292-3.
  • Mughal, Z., Sood, M., Ward, K.A., Adams, J.E. Pathogenesis of bone disease in cystic fibrosis: The role of bone size and sarcopenia. Journal of the Royal Society of Medicine.2006:S99 (46), 2-5.
  • Smith CR, Miranda A, Rudolph CD, Sood MR. Removal of impacted food in children with eosinophilic esophagitis using Saeed banding device. J Pediatr Gastroenterol Nutr. 2007;44:521-3.
  • Venkatasubramani N, Rudolph CD, Sood MR. Erythromycin lacks colon prokinetic effect in children with functional gastrointestinal disorders: a retrospective study. BMC Gastroenterol. 2008:21;8:38.
  • Altaf MA, Rudolph, CD, Werlin SL, Sood MR, Colonic volvulus in children with intestinal motility disorders: A diagnostic dilemma. J Pediatr Gastroenterol Nutr.J Pediatr Gastroenterol Nutr, 2009;49(1):59-62.
  • Kaugars AS, Silverman A, Kinservik M, Heinze S, Reinemann L, Sander M, Schneider B, Sood M. Families' perspectives on the effect of constipation and fecal incontinence on quality of life. J Pediatr Gastroenterol Nutr. 2010;51(6):747-52.
  • Mickle A, Sood M, Zhang Z, Shahmohammadi G, Sengupta JN, Miranda A. Antinociceptive effects of melatonin in a rat model of post-inflammatory visceral hyperalgesia: a centrally mediated process. Pain. 2010;149(3):555-64. 
  • Ogden CA, Akobeng AK, Abbott J, Aggett P, Sood M, Thomas AG. Validation of an instrument to measure quality of life in British children with inflammatory bowel disease, J Pediatr Gastroenterol Nutr, J Pediatr Gastroenterol Nutr.2011;53:280-286.
  • Sood MR, Di Lorenzo C, Hyams J, Miranda A, Simpson P, Mousa. H, Nurko S. Beliefs and Attitudes of General Pediatricians and Pediatric Gastroenterologists Regarding Functional Gastrointestinal Disorders Ð A Survey Study. Clinical Pediatric. Clin Pediatr (Phila). 2011 Apr 4. [Epub ahead of print]
  • Tipnis NA, El-Chammas KI, Rudolph CD, Werlin SL, Sood M. Do Oral-Anal Transit Markers Predict Which Children Would Benefit From Colonic Manometry Studies? J Pediatr Gastroenterol Nutr. 2011 Jul 4. [Epub ahead of print] 
  • Sood M, Mousa H, Tipnis N, Di Lorenzo C, Werlin S, Fernandez S, Liem O, Simpson P, Rudolph C. Inter-observer variability in the interpretation of colon manometry studies in children, J Pediatr Gastroenterol Nutr. In press
  • Venkatasubraman N, Verbsky JW, Rudolph C, Sood M. Hemophagocytic lymphohistiocytosis with multi-organ involvement in children with chronic intestinal pseudo-obstruction receiving parenteral nutrition support. Jr Pediatr Gastroenterol Nutr. In press. 
  • Ramprasad J, Sood M, Takahashi T. Up-regulated cystic fibrosis transmembrane conductance regulator following anal stenosis in rats. J Ped Surgery. In press

Book chapters

  • Sood M, Booth IW. Is prolonged rotavirus infection a common cause of protracted diarrhoea? Arch Dis Child 1999;80:309-310.
  • Sood M, Booth IW. Malabsorption in children. International Journal of Gastroenterology 2000;5:15-17.
  • Hyman PE, Sood M Chronic intestinal pseudo-obstruction. NORD Guide to Rare Disorders, 2002.
  • Sood M, Hyman PE. Intestinal Motility Disorders in Mark D. Stringer, Pierre D. E. Mouriqu, Keith T. Oldham, Edward R. Howard editors, Pediatric Surgery and Urology: Long Term Outcomes, 1st ed. Cambridge University Press 2006. p. 416-428. 
  • Sood M, Rudolph C. Gastroesophageal Reflux in Adolescent. Adolesc Med Clin. 2004;15(1):17- 36. Sood M, Rudolph C. Achalasia and Other Motor Disorders. In Wyllie R, Hyams J, Kay M, editors: Pediatric Gastrointestinal and Liver Disease, 3rd ed. Philadelphia: WB Saunders; 2006.
  • Narayanan V, Sood M R. Motility Disorders in Children, Indian J Pediatr, 2006;73(10):927-30.
  • Sood M. Malabsorption Disorders in Childhood. Kliegman RM, Behrman RE, Jenson HB, Stanton BF, editors, Nelson Textbook of Pediatrics, 18th ed. Philadelphia: Elsevier; 2007. P 1587-1599.
  • Miranda A, Sood M R. Therapy for recurrent abdominal pain. Current Treatment Options in Gastroenterology. 2006;9(5):409-15.
  • Sood M, Rudolph C. Achalasia. In Liacouras & Piccoli editors, Pediatric Gastroenterology-Requisites in Pediatrics, 1st ed. Philadelphia, Mosby Inc; 2008. p. 13-18.
  • Sood M. Irritable Bowel Syndrome. In Mamula P, Markowitz J, Baldassano B, editors, Pediatric Inflammatory Bowel Disease, 1st ed. New York: Springer; 2008:581-589.
  • Sood M, Rudolph CD. Gastrointestinal motility disorders in adolescent patients: transitioning to adult care. Gastroenterol Clin North Am. 2007;36(3):749-63.
  • Sood M, Rudolph C. Evaluation and management of common problems after fundoplication. Indian Journal of Paediatrics. 2008;75:S10-14. 
  • Altaf MA, Sood M. The nervous system and gastrointestinal function. Developmental Disabilities Research Reviews. 2008;14:87-95.
  • Sood M. Treatment approaches to irritable bowel syndrome. Pediatr Ann. 2009;38(5):272-6.
  • Sood MR, Rudolph C. Achalasia and Other Motor Disorders. In Wyllie R, Hyams J, Kay M, editors: Pediatric Gastrointestinal and Liver Disease, 3rd ed, Philadelphia: WB Saunders; 20011. p. 248-254.
  • Sood M. Approach to a child with constipation and fecal incontinence. In Rudolph CD, Rudolph AM, Lister GE, First LR, Gershon AA, editors, RudolphÕs Pediatrics. 22nd ed. New York: McGraw Hill; 2011. p. 1386-1388.
  • Calkins C, Sood M. Congenital anomalies of the Anorectum. In Rudolph CD, Rudolph AM, Lister GE, First LR, Gershon AA, editors, RudolphÕs Pediatrics. 22nd ed. New York: McGraw Hill; 2011. p. 1480-1482.
  • Sood M, Calkins C. Motor Disorders of the Stomach, Small Bowel, and Colon. In Rudolph CD, Rudolph AM, Lister GE, First LR, Gershon AA, editors, RudolphÕs Pediatrics. 22nd ed. New York: McGraw Hill; 2011. p. 1433-143.