Shim, Katherine

Titles
Investigator, Children's Research Institute; assistant professor, Pediatrics, Cell Biology, Neurobiology and Anatomy, and Otolaryngology and Communications Sciences, The Medical College of Wisconsin.

Division
Genetics

Research center/program
Regenerative Medicine and Developmental Biology

Research interests
Cell and developmental biology, ear diseases, deafness, environmental health, genetic diseases/genomics.

Study interests
Hearing and balance, neurodegeneration, mouse genetics, birth defects.

Education
Doctorate, Stanford University, Palo Alto, CA, 2001; post-doctoral fellowship, University of California, San Francisco, 2001-2007.

Representative publications

  • Shim K, Blake KJ, Jack J, Krasnow MA. The Drosophila Ribbon Gene Encodes a Nuclear BTB Domain Protein that Promotes Epithelial Migration and Morphogenesis. Development. 2001; 128:4923-4933.
  • Shim K, Minowada G, Coling DE, Martin GR. Sprouty2, A Mouse Deafness Gene, Regulates Cell Fate Decisions in the Auditory Sensory Epithelium by Antagonizing FGF Signaling. Developmental Cell. 2005; 8:553-564.
  • Shim K. The Auditory Sensory Epithelium: The Instrument of Sound Perception. International Journal of Biochemistry and Cell Biology. 2006; 38:1827-33.
  • Mahoney Rogers AA, Zhang J, Shim K. Sprouty1 and Sprouty2 limit both the Size of the Otic Placode and Hindbrain Wnt8a by Antagonizing FGF Signaling. Developmental Biology. 2011; 94-104.
  • Shim K.  Vibratome Sectioning for Enhanced Preservation of the Cytoarchitecture of the Mammalian Organ of Corti. Journal of Visualized Experiments. 2011; 52.

Grants

  • Genetic Analysis of the Induction and Morphogenesis of the Inner Ear, National Institutes of Health, principal investigator.
  • Genetic Analysis of Degeneration of the Olfactory Epithelium, NIEHS Children's Environmental Health Sciences Core Center, principal investigator.

Contact
Children's Research Institute
8701 Watertown Plank Road
Wauwatosa, WI 53226
Phone: (414) 955-2444
Fax: (414) 955-6329
E-mail: kshim@mcw.edu

Investigator in the areas of: