Katherine Shim, PhD
Titles
Investigator, Children's Research Institute; assistant professor, The Medical College of Wisconsin.
Division
Genetics
Research center/program
Regenerative Medicine and Developmental Biology
Research interests
Cell and developmental biology, genetic diseases/genomics
Study interests
Hearing and balance, mouse genetics, birth defects, embryogenesis.
Education
Doctorate, Stanford University, 2001; post-doctoral fellowship, University of California, San Francisco, 2001-2007.
Representative publications
- Shim K. The Auditory Sensory Epithelium: The Instrument of Sound Perception. International Journal of Biochemistry and Cell Biology. 2006; 38:1827-33.
- Shim K, Minowada G, Coling DE, Martin GR. Sprouty2, A Mouse Deafness Gene, Regulates Cell Fate Decisions in the Auditory Sensory Epithelium By Antagonizing FGF Signaling. Developmental Cell. 2005; 8:553-564.
- Shim K, Blake KJ, Jack J, Krasnow MA. The Drosophila Ribbon Gene Encodes a Nuclear BTB Domain Protein That Promotes Epithelial Migration and Morphogenesis. Development. 2001; 128:4923-4933.
- Shim K. Vibratome sectioning for enhanced preservation of the cytoarchitecture of the mammalian organ of Corti. J Vis Exp. 2011; Jun 17(52).
- Mahoney Rogers AA, Zhang J, Shim K. Sprouty1 and Sprouty2 limit both the size of the otic placode and hindbrain Wnt8a by antagonizing FGF signaling. Dev Biol. 2011 May 1;353(1):94-104.
Grants
- Sprouty Gene Function in Mouse Inner Ear Development, National Institutes of Health, principal investigator.
- Genetic Analysis of the Induction and Morphogenesis of the Inner Ear, National Institutes of Health, principal investigator.
Contact
Children's Research Institute
8701 Watertown Plank Road
Wauwatosa, WI 53226
Phone: (414) 955-2444
Fax: (414) 955-6329
E-mail: kshim@mcw.edu
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