Mitchell H. Grayson, MD

Titles
Pediatric asthma/allergist, Children's Hospital of Wisconsin; associate professor of Pediatrics, Medicine, Microbiology and Molecular Genetics, The Medical College of Wisconsin.

Division
Asthma, allergy and immunology

Research interests
Allergies, disease pathology, respiratory diseases, asthma.

Study interests
Asthma, atopy, dendritic cells, lung, virus, respiratory infection, food allergy.

Education
Medical degree, University of Chicago/Pritzker School of Medicine, Ill., 1993; residency, Internal Medicine, Hospital of the University of Pennsylvania, Philadelphia, 1993-1995; fellowship, Allergy and Immunology, Johns Hopkins University, Baltimore, Md., 1995-1998.

Certifications
American Board of Allergy and Immunology (exp 2019).

Honors
Phi Beta Kappa, 1989; Sigma Xi, 1989;  National Institutes of Health Student Summer Research Award, 1989; elected to Fellow of the American Academy of Allergy, Asthma and Immunology, 1998; Pharmacia Fellowship Award, 1999; New Outstanding Volunteer - American Lung Association of Eastern Missouri, 2001; Saturday Service Award - presented by the Washington University Medical Students for service in the free clinic they run, the Saturday Neighborhood Health Center, 2001; American Academy of Allergy, Asthma, and Immunology Interest Section Award, 2004; Professor Pro Tempore, The University of Mississippi Medical Center School of Medicine, department of Medicine, 2007; Orchid Award - Asthma and Allergy Foundation of America, Saint Louis Chapter, 2007; elected to Fellow of the American College of Allergy, Asthma and Immunology, 2007; Grant reviewer for NIH Study Sections, Dept. of Defense, and various foundation agencies, 2008 - present; voted Best Doctor, 2009-2010; voted Best Doctor in America, 2011-2012;  inducted into the Collegium Internationale Allergologicum, 2010; Alain I deWeck Travel Grant awardee, 28th symposium of the Collegium Internationale Allergologicum, 2010; named one of America's Top Physicians in Allergy and Immunology, Consumers' Research Council of America, 2011; selected as a Top Allergist/Immunologist by the International Association of Healthcare Professionals (IAHCP). Spotlighted in the Leading Physicians of the World, 2011.

Representative publications

  • Grayson MH, Cheung D, Rohlfing MM, Kitchens R, Spiegel DE, Tucker J, Battaile JT, Alevy Y, Yan L, Agapov E, Kim EY, Holtzman MJ. Induction of High-affinity IgE Receptor on Lung Dendritic Cells During Viral Infection Leads to Mucous Cell Metaplasia. Journal of Experimental Medicine. 2007; 204:2759-2769.
  • Grayson MH, Ramos MS, Rohlfing MM, Kitchens R, Wang HD, Gould A, Agapov E, Holtzman MJ. Controls for Lung Dendritic Cell Maturation and Migration During Respiratory Viral Infection. Journal of Immunology. 2007; 179:1438-48.
  • Khan SH, Grayson MH. Cross-linking IgE Augments Human Conventional Dendritic Cell Production of CCL28. Journal Allergy Clin Immunol. 2010; 125:265-267.
  • Cheung DS, Ehlenbach SJ, Kitchens RT, Riley DA, Thomas LL, Holtzman MJ, Grayson MH. Cutting edge: CD49d+ Neutrophils Induce FeeRI Expression on Lung Dendritic Cells in a Mouse  Model of Postviral Asthma. Journal Immunol.
    2010; 185(9):4983-4987.
  • Cheung DS, Ehlenbach SJ, Kitchens T, Riley DA, Grayson MH. Development of Atopy by Severe Paramyxoviral Infection in a Mouse Model. Ann Allergy Asthma Immunol. 2010; 105(6):437-443.
  • Chen X, Leach D, Hunter DA, Sanfelippo D, Buell EJ, Zemple SJ, Grayson MH. Characterization of Intestinal Dendritic Cells in a Murine Norovirus Infection. The Open Immunol. Journal. 2011. In press.

 Grants

  • National Institutes of Health, RO1 HL087778, Dendritic Cells in Atopic and Virus-induced Airway Disease, principal investigator.
  • NIH, R21 A1079905, Induction of Food Allergy by Intestinal Dendritic Cells, principal investigator.
  • Genetech Inc., Developmental Expression of Dendritic Cell FceRI, principal investigator.
  • Children's Research Institute, Studies of Novel Pathway Translating Viral Infection into Allergic Disease, principal investigator.
  • National Institutes of Health, R21 AI079905-02S1, Induction of Food Allergy by Intestinal Dendritic Cells, (summer student ARRA supplement),  principal investigator.
  • National Institutes of Health, RO1 HL087778-02S1, Dendritic Cells in Atopic and Virus-induced Airway Disease, (ARRA supplement) principal investigator.
  • Children's Research Institute, Virus and Atopic diseases, principal investigator.

Contact
Children's Research Institute
8701 Watertown Plank Road
Wauwatosa, WI 53226
Phone: (414) 456-5648
Fax: (414) 456-6323
E-mail: mgrayson@mcw.edu