Rashmi Sood, PhD

Title
Assistant professor, Pediatric pathology, Children's Research Institute, Medical College of Wisconsin.

Division
Pathology

Research interests
Bleeding/blood disorders, disease pathology, fetal concerns/prematurity, genetic disease/genomics, cell/developmental biology.

Study interests
Thrombophilia-associated pregnancy disorders; placental vascular health, placental regulation of maternal cardiovascular function.

Education
Doctorate, Tata Institute of Fundamental Research, University of Bombay, India, 1993; postdoctoral fellowship, Blood Research Institute, Blood Center of Wisconsin, Milwaukee, Wis., 2000-2002.

Honors
University of Delhi Merit Scholarship Award; winner of National Research Scholarship of the University Grants commission, India; Research Scholar Fellowship awarded by the Tata Institute of fundamental Research, Bombay, India.

Representative publications

• Isermann BH, Sood R, Pawlinski R, Zogg M, Kalloway S, Degen JL, Mackman N, and Weiler H. The Thrombomodulin-protein C system is Essential for the Maintenance of Pregnancy. Nature Medicine. 2003; 9(3):331-337.
• Sood R and Weiler H. Embryogenesis and Gene Targeting of Coagulation Factors in Mice. Best Practice in Research and Clinical Haematology. 2003; 16(2):169-81.
• Sood R, Kalloway S, Mast AE, Hillard CJ and Weiler H. Fetomaternal Cross Talk in the Placental Vascular Bed:  Control of Coagulation by Trophoblast Cells. Blood. 2006; 107(8):3173-80. [Article accompanied by invited editorial commentary. Gris J-C: Trophoblast cells sense maternal hemostasis. Blood. 2006; 107(8):3019-20].
• Sood, R*, Zogg M, Westrick RJ, Guo Y, Kerschen EJ, Girardi G, Salmon JE, Coughlin SR and Weiler H*. Fetal Gene Defects Precipitate Platelet Mediated Pregnancy Failure in Factor V Leiden mothers. Journal of Experimental Medicine. 2007; 204(5):1049-56 (*Co-Corresponding authors).  [Article accompanied by editorial news story:  Avoiding Fetal Loss. Journal of Experimental Medicine. 2007; 204(5):966].
• Maroney SA, Cooley BC, Sood R, Weiler H and Mast AE. Combined Tissue Factor Pathway Inhibitor and Thrombomodulin Deficiency Produces an Augumented Hypercoagulable State with Tissue Fibrin Deposition. Journal of Thrombosis and Haemostasis. 2008; 6(1):111-7.
• Sood R*, Sholl L, Isermann B, Zogg M, Coughlin SR and Weiler H*. Maternal Par4 and Platelets Contribute to Defective Placenta Formation in Mouse Embryos Lacking Thrombomodulin. Blood. 2008; 112(3):585-91. (*Co-Corresponding authors).

Contact information
Children's Research Institute
8701 Watertown Plank Road
Milwaukee, WI 53226
Phone: (414) 955-2451
Fax: (414) 955-6307
E-mail: rsood@mcw.edu