Qing (Robert) Miao, PhD                  

Titles
Investigator, Chidlren's Research Institute; assistant professor, Pediatrics (Surgery and Pathology), The Medical College of Wisconsin.

Division
Pathology, Surgery

Research interests
Birthmarks and vascular anomalies, Cancer, cell and developmental biology, disease pathology.

Education
Doctorate, Medical University of South Carolina, Charleston, 1997-2002; postdoctoral fellowship, Yale University School of Medicine, New Haven, Conn.; 2002-2006.

Honors
ATVB Conference Merit Award for Young Investigators, American Heart Association's Council on Arteriosclerosis, Thrombosis and Vascular Biology, 2006; Scientist Development Awards, American Heart Association National Program, 2007; ATVB Conference Merit Award for Young Investigators, American Heart Association's Council on Arteriosclerosis, Thrombosis and Vascular Biology, 2010.

Representative publications

  • Miao RQ, Agata J, Chao L, Choa J. Kallistatin is a New Endogenous Inhibitor of Angiogenesis and Tumor Growth. Blood. 2002; 100:3245-3252. PMID: 12384424
  • Acevedo L, Yu J, Erdjument-Bromage H, Miao RQ, Kim JE, Fulton D, Tempst P, Strittmatter SM, Sessa WC. A New Role for Nogo as a Regulator of Vascular Remodeling. Nature Medicine. 2004; 10:382-388. PMID: 15034570
  • Miao RQ, Gao Y, Harrison KD, Prendergast J, Acevedo LM, Yu J, Hu F, Strittmatter SM, Sessa WC. Identification of a Receptor Necessary for Nogo-B Stimulated Chemotaxis of Endothelial Cells. Proceedings of the National Academy of Sciences of the United States of America. 2006; 103:10997-11002. PMID: 16835300.
  • Miao RQ, Fontana J, Fulton D, Lin MI, Harrison KD, Sessa WC. Dominant-negative Hsp90 Reduces VEGF-stimulated Nitric Oxide Release and Migration in Endothelial Cells. Arteriosclerosis, Thrombosis and Vascular Biology. 2008; 28:105-111. PMID: 17975117
  • Harrison KD, Miao RQ, Fernandez-Hernando C, Suarez Y, Davalos A, Sessa WC. Nogo-B Receptor Stabilizes Niemann-Pick Type C2 Protein and Regulates Intracellular Cholesterol Trafficking. Cell Metabolisum. 2009; 10(3): 208-18. PMID: 19723497.
  • Zhao, B, Chun CZ, Liu, Z, Horswill MA, Pramanik K, Wilkinson GA, Ramchandran R, Miao, RQ.* Nogo-B Receptor is Essential for in Vivo Angiogenesis in Zebrafish via Akt Pathway. Blood. 2010;116(24) 5423-5433. *Corresponding author. PMID: 20813898.

Grants

  • Role of NgBR, National Institutes of Health, National Heart, Lung and Blood Institute, principal investigator.
  • Nogo-B Receptor Modulates Sensitivity of Breast Cancer Cells to Chemotherapy and Radiation Therapy, State of Wisconsin Tax Check-off Program for Breast & Prostate Cancer Research, principal investigator.
  • Roles of Nogo-B and Nogo-B Receptor (NgBR) in Tumor and Angiogenesis, American Cancer Society Pilot Research Grant, MCW Cancer Center, principal investigator.

Contact
Children's Research Institute
8701 Watertown Plank Road
C4445
Wauwatosa, WI 53226-0099
Phone: (414) 955-5701
Fax: (414) 955-6473
E-mail: qmiao@mcw.edu

Investigator in the areas of: