James Tweddell, MD

Titles
Medical director, Cardiothoracic Surgery, Children's Hospital of Wisconsin; professor, Surgery (Cardiothoracic), and chair, Cardiothoracic Surgery, Medical College of Wisconsin.

Division
Cardiothoracic Surgery

Research center/program
Cardiothoracic Surgery

Research interests
Heart disease

Study interests
Cardiopulmonary bypass, pediatric cardiac critical care, pediatric cardiac surgery.

Education
Medical degree, University of Cincinnati College of Medicine, Ohio, 1985; intern and resident, General Surgery, New York University Medical Center, 1987; research fellow, Cardiothoracic Surgery, Washington University Medical Center, St. Louis, 1989; senior resident and chief resident, General Surgery, Washington University Medical Center, St. Louis, 1991; resident, Cardiothoracic Surgery, Washington University Medical Center, St. Louis, 1993; fellow, Pediatric Cardiothoracic Surgery, Washington University Medical Center, St. Louis Children's Hospital, 1993.

Honors
Alpha Omega Alpha, University of Cincinnati College of Medicine, 1985; Fleischmann Scholarship, University of Cincinnati College of Medicine, 1983; Lange Medical Publications Award, University of Cincinnati College of Medicine, 1985.

Representative publications

• Baker JE, Kozik D, Hsu AK, Fu X, Tweddell JS, Gross GJ. Darbepoetin Alfa Protects the Rat Heart Against Infarction: Dose-response, Phase of Action and Mechanisms. Journal of Cardiovascular Pharmacology. 2007; 49(6):337-45.
• Frommelt PC, Sheridan DC, Mussatto KA, Hoffman GM, Ghanayem NS, Frommelt MA, Tweddell JS. Effect of Shunt Type on Echocardiographic Indices After Initial Palliations for Hypoplastic Left Heart Syndome: Blalock-Taussig Shunt Versus Right Ventricle-pulmonary Artery Conduit. Journal of American Society Echocardiograph. 2007 Jun. 29.
• Tweddell JS. Aspirin: A Treatment for the Headache of Shunt-dependent Pulmonary Blood Flow and Parallel Circulation? Circulation. 2007 Jul. 17; 116(3):236-7.
• Ghanayem NS, Berger S, Tweddell JS. Medical Management of the Failing Fontan. Pediatric Cariology. 2007 Aug. 31.
• Baker JE, Su J, Fu X, Hsu A. Gross GJ, Tweddell JS, Hogg N. Nitrite Confers Protection Against Myocardial Infarction: Role of Xanthine Oxidoreductase, NADPH Oxidase and K(ATP) Channels. Journal Molecular Cell Cardiology. 2007 Jul. 31.
• Tweddell JS, Ghanayem NS, Mussatto KA, Mitchell ME, Lamers LJ, Musa NL, Berger S, Litwin SB, Hoffman GM. Mixed Venous Oxygen Saturation Monitoring After Stage 1 Palliation for Hypoplastic Left Heart Syndrome. Annals of Thoracic Surgery. Accepted.

Contact
Children's Hospital of Wisconsin
Herma Heart Center
PO Box 1997
Milwaukee, WI 53201-1997
Phone: (414) 266-2638
E-mail: jtweddel@chw.org