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	Overview of Primary Immunodeficiency Program

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Dennis W. Schauer, Jr., MT(ASCP)

Administrative/Technical Director, Clinical Immunodiagnostic and Research Laboratory, Department of Pediatrics

Specialties:

Bone Marrow Transplantation
Clinical Flow Cytometry
Immune Dysregulation
Pediatric Oncology
Primary Immune Deficiencies

Education/training:

BA: Lakeland College
Research Externship: Marquette University
Clinical Internship: St. Vincent Hospital
Biochemical Internship: Plastics Engineering Co.
Biotechnology Internship: Dupont/ConAgra

Professional memberships/societies/committees:

American Society for Clinical Pathology (ASCP)
Clinical Cytometry Society (CCS)
Flow Informatics and Computational Cytometry Society (FICCS)

Recent or important publications:

1. Whitsett J, Martasek, P, Zhao H, Schauer DW, Hatakeyama K, Kalyanaraman B, Vasquez-Vivar J. Endothelial cell superoxide anion radical generation is not dependent on endothelial nitric oxide synthase-serine 1179 phosphorylation and endotherlial nitric oxide synthase dimer/monomer distribution. Free Radical Biology and Medicine, 40(11): 2056-2068 (2006).

2. Grossman WJ, Mohammed R, Schauer DW, Gerday E, Grose C, Goldman F. Development of hemophagocytic lymphohistiocytosis in triplets infected with HHV-8. Blood, 106: 1203-1206 (2005).

3. Gershan JA, Johnson BD, Weber J, Schauer DW, Natalia N, Behnke S, Burns K, Maloney KW, Warwick AB, Orentas RJ. Immediate transfection of patient-derived leukemia: A novel source for generating cell-based vaccines. Genetic Vaccines and Therapy, 3:4 (21 June 2005).

4. Rosenblum MD, Labelle JL, Chang CC, Margolis DA, Schauer DW, Vesole DH. Efficacy of alemtuzumab treatment for refractory T Cell large granular lymphocytic leukemia. Blood, 1: 1969-1971 (2004).

5. Orentas RJ, Schauer DW, Ellis FW, Walczak J, Casper JT, Margolis DA. Monitoring and modulation of Epstein-Barr virus loads in pediatric transplant patients. Pediatric Transplantation, 7: 305-314 (2003).

6. Johnson BD, Schauer DW, Yan X, Orentas RJ. Dual expression of CD80 and CD86 produces a tumor vaccine superior to single expression of either moleclue. Cellular Immunology, 222: 15-26 (2003).

7. Bin Q, Johnson BD, Schauer DW, Orentas RJ. Production of macrophage migration inhibitory factor (MIF) by human and murine neuroblastoma. Tumor Biology, 23: 123-129 (2002).

8. Orentas RJ, Schauer DW, Bin Q, Johnson BD. Electrofusion of a weakly immunogenic neuroblastoma with dendritic cells produces a tumor vaccine. Cellular Immunology, 213: 4-13 (2001).