Andrew K. Tryba, PhD 

Titles
Investigator, Children's Research Institute; assistant professor, Physiology, Medical College of Wisconsin.

Division
Physiology

Research center/program
Neuroscience research

Research interests
Neuropsychiatric diseases, sleep disorders

Study interests
Locomotion, pediatric epilepsy, Rett Syndrome, rhythm generation underlying epilepsy and breathing, sudden infant death syndrome.

Education
Doctorate, Case Western Reserve University, Cleveland, Ohio, 2000; postdoctoral, University of Chicago, 2004.

Honors
Texas Tech University President, Dean's Honor Roll, 1990; Case Western Reserve University Graduate Dean's Instructional Excellence Award, 1995; Case Western Reserve University Graduate School Dean's letter for "exceptionally high level of academic achievement," 2000.

Research publications

  • Tryba AK, Peña F, Ramirez JM. Gasping Activity in vitro: A Rhythmic Behavior Dependent on 5HT2A Receptors. Journal of Neuroscience. 2006; 26(10):2623-2634.
  • Selected as "Recommended Reading" by Faculty of 1000.
  • Reviewed as being "Of Outstanding Interest" in Current Opinion in Neurobiology, 16:604-614.
  • Referenced in American Medical Association 2006 guidelines for fighting SIDS.     
  • Viemari J-CT, Roux J-CT, Tryba AK, Saywell V, Burnet H, Pena F, Zanella S, Bevengut M, Barthelemy-Requin M, Herzig LB, Moncla A, Mancini J, Ramirez J-M, Villard L, Hilaire G. Mecp2 Deficiency Disrupts Norepinephrine and Respiratory Systems in Mice: Implications for Rett Syndrome. Journal of Neuroscience. 2005 Decc 14; 25(50):11521-30. (TThere are two first authors on this paper).
  • Ramirez JM, Tryba AK, Peña F. Pacemaker Neurons and Neural Networks: An Integrative View. Current Opinion in Neurobiology. 2004; 14:1-10.
  • Pena F, Parkis MA, Tryba AK, Ramirez JM. Differential Contribution of Pacemaker Properties to the Generation of Respiratory Rhythms during Normoxia and Hypoxia. Neuron. 2004; 43(1):105-117.
  • Selected as a "Must Read" by Faculty of 1000.
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  • Tryba AK, Pena F, Ramirez JM. Stabilization of Bursting in Respiratory Pacemaker Neurons. Journal of Neuroscience. 2003; 23(8):3538.
  • Tryba AK, Ramirez JM. Background Sodium Current Stabilizes Bursting in Respiratory Pacemaker Neurons. Journal of Neurobiology. 2004; 60(4):418-489. 
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    Research in popular media (selected examples)

    • Scientific American Frontiers TV Program: Natural Born Robots: Robo-roach, Host: Alan Alda (2000).
    • Discovery Magazine Technology Awards competition finalist: Robotic Cockroach Project (2000).
    • "The Drive at Five" Radio, interviewed live on Toronto Canada Radio: Understanding SIDS (2004).
    • The Chicago Tribune: Interviewed by senior science editor Sunday's edition feature article regarding neuron article (2004).
    • Frontiers in Medicine-Discovery Channel program highlighting epilepsy project (2004).
    • Milwaukee Journal Sentinel, Pulse science section feature article, "Research team makes key finding in battling SIDS." (2006). 
    • American Medical Association, AP press release, "New guidelines for fighting SIDS" 25 May 2006.
    • The Boston Globe, interviewed by Carey Goldberg, Globe Staff for AP press-related article "Brain defects linked to sudden infant death," 1 Nov., 2006.

    Grants

    • Background Sodium Currents in Respiratory Pacemakers, Francis B. Parker fellowship, principal investigator.
    • Background Sodium Currents in Respiratory Pacemakers, National Institutes of Health PHS 398 (ROI) grant, principal investigator.

    Contact
    Children's Research Institute
    8701 Watertown Plank Road
    Wauwatosa, WI 53226
    Phone: (414) 456-4975
    Fax: (414) 456-6546
    E-mail: atryba@mcw.edu

    Investigator in the areas of: