Brian D. Shames, MD 

Titles
Medical director, Pediatric Transplantation, Children's Hospital of Wisconsin; assistant professor, Surgery, Medical College of Wisconsin.

Division
Transplant Surgery

Research interests
Solid organ transplantation

Study interests
Ischemia-reperfusion injury, pediatric liver transplant, solid organ transplant, outcomes.

Education
Medical degree, University of Connecticut, Farmington, 1994; residency, General Surgery, University of Colorado Health Sciences Center, Denver, 2001; fellowship, Transplant Surgery, University of Wisconsin-Madison, 2004.

Certifications
American Board of Surgery, 2001; Transplant Surgery, 2004.

Representative publications

• Foley DP, Fernandez LA, Leverson G, Chin LT, Krieger N, Cooper JT, Shames BD, Becker YT, Odorico JS, Knechtle SJ, Sollinger HW, Kalayoglu M, D'Alessandro AM. Donation after Cardiac Death: The University of Wisconsin Experience with Liver Transplantation. Annals of Surgery. 2005; 242(5):724-31.
• Shames BD, Barton HH, Reznikov LL, Cairns CB, Banerjee A, Harken AH, Meng X. Ischemia Alone is Sufficient to Induce TNF-alpha mRNA and Peptide in the Myocardium. Shock. 2002; 17(2):114-9.
• Shames BD, D'Alessandro AM, Pirsch JD, Knechtle SJ, Odorico JS, Becker YT, Kalayoglu M, Chin LT, Sollinger HW. Living-unrelated Renal Transplantation at the University of Wisconsin. Clinical Transplant. 2001; 149-56.
• Shames BD, Fernandez LA, Sollinger HW, Chin LT, D'Alessandro AM, Knechtle SJ, Lucey MR, Hafez R, Musat AI, Kalayoglu M. Liver Transplantation for HELLP Syndrome. Liver Transplant. 2005; 11(2):224-8.
• Shames BD, Meldrum DR, Selzman CH, Pulido EJ, Cain BS, Banerjee A, Harken AH, Meng X. Increased Levels of Myocardial IkappaB-alpha Protein Promote Tolerance to Endotoxin. American Journal of Physiology. 1998; 275(3 Pt 2):H1084-91.
• Shames BD, Odorico JS, D'Alessandro AM, Pirsch JD, Sollinger HW. Surgical Repair of Transplant Renal Artery Stenosis with Preserved Cadaveric Iliac Artery Grafts. Annals of Surgery. 2003; 237(1):116-22.
• Shames BD, Zallen GS, McIntyre, Jr. RC, Bensard DD, Pulido EJ, Miller SA, Pomerantz BJ, Selzman CH, Meng X, Harken AH. Chemokines as Mediators of Diseases Related to Surgical Conditions. Shock. 2000; 14(1):1-7.

Grants

• Froedtert Hospital Foundation: Role of Tyrosine Nitration Following Hypothermic Ischemic Injury on the Development of Chronic Allograft Nephropathy, principal investigator, 11/28/2005-11/27/2006.
• American Heart Association, Midwest Affiliate, Grant in Aid: Therapeutics to Treat Vascular Injury Using Alternative Pseudo-typed Lentiviral Vectors, co-investigator, 1/01/2006-12/31/2008.

Contact
Children's Hospital of Wisconsin
PO Box 1997
Milwaukee, WI 53201-1997
Phone: (414) 456-6920
Fax: (414) 456-6222
E-mail: bshames@mcw.edu