Tara L. Sander, PhD

Titles
Investigator, Children's Research Institute; assistant professor, Pediatric Surgery, Medical College of Wisconsin.

Division
Surgery

Research interests
Cell and developmental biology

Study interests
Endothelial cells function, transcriptional regulation, vascular biology.

Education
Doctorate, Medical College of Wisconsin, Milwaukee, 2000; surgery research fellow, Children's Hospital Boston, Harvard Medical School, 2001; pathology research fellow, Children's Hospital Boston, Harvard Medical School, 2003.

Honors
Joseph E. Collie merit award, Beloit College; First Place Poster Award, 10th Chicago Signal Transduction Symposium; Outstanding Poster Presentation, Medical College of Wisconsin; AACR-WICR Brigid G. Leventhal Scholar Award; Children's Hospital of Wisconsin Research Foundation Award, Children's Research Institute; Research Affairs Committee Award, Medical College of Wisconsin; American Cancer Society Institutional Research Award.

Representative publications

• Sander TL, Haas AL, Peterson MJ, Morris JF. Identification of a Novel SCAN Box Related Protein that Interacts with MZF1B: The Leucine-rich SCAN Box Mediates Hetero- and Homoprotein Associations. Journal of Biological Chemistry. 2000; 275:12857-12867.
• Johnson EN, Lee YM, Sander TL, Kaushal S, Rabkin E, Schoen FJ, Bischoff J. An NFATc1-dependent Pathway for VEGF-mediated Proliferation in Human Pulmonary Valve Endothelial Cells. Journal of Biological Chemistry. 2003; 278(3):1686-1692.
• Sander TL, Stringer KF, Maki JL, Szauter P, Stone JR, Collins T. The SCAN Domain Defines a Large Family of Zinc Finger Transcription Factors. Gene. 2003; 310:29-38.
• Klinkner DB, Densmore JC, Kaul S, Noll L, Lim HJ, Weihrauch D, Pritchard KA, Oldham KT, Sander TL. Endothelium-derived Microparticles Inhibit Human Cardiac Valve Endothelial Cell Function. Shock. In press.
• Klinkner DB, Lim HJ, Strawn EY, Oldham KT, Sander TL. An in vivo Murine Model of Rosiglitazone use in Pregnancy. Fertility and Sterility. In press.
• Sander TL, Noll L, Klinkner DB, Weihrauch D, He BJ, Kaul S, Zangwill SD, Tweddell JS, Pritchard KA, Oldham KT. Rosiglitazone Antagonizes VEGF Signaling and NFATc1 Activation in Cardiac Valve Endothelium. Endothelium (Journal of Endothelial Research). In press.

Grants

• Characterization of the Cancer-suppressor Gene MZF1: The Role of RAZI Binding on Transcriptional Function, American Cancer Society, principal investigator.
• Native LDL, Cholesterol and Impaired Vasorelaxation, National Institutes of Health Heart Lung and Blood Institute, co-principal investigator.

Contact
Children's Research Institute
8701 Watertown Plank Road
Wauwatosa, WI 53226
Phone: (414) 456-5807
Fax: (414) 456-6473
E-mail: sandert@mcw.edu