Nancy J. Wandersee, PhD           

Titles
Investigator, Children's Research Institute; assistant professor, Medical College of Wisconsin.       

Division
Hematology, Oncology and Transplant

Research interests
Bleeding and blood disorders

Study interests
Hemolytic anemia, hereditary spherocytosis and elliptocytosis, mouse models, pathophysiology of stroke, red blood cell membrane/membrane skeleton, thrombosis.

Education
Doctorate, Genetics, University of Iowa, Iowa City, 1995; post-doctoral fellowship, Red Blood Cell Research, The Jackson Laboratory, Bar Harbor, Maine, 1995-2001.  

Honors
Phi Kappa Phi National Honor Society and Gamma Sigma Epsilon Chemistry Honor Society, 1986; Outstanding Undergraduate Research Award, Sigma Xi Scientific Research Society, 1986; member Sigma Xi Scientific Research Society 1986–present; member American Association for the Advancement of Science, 1997–present; member American Society of Hematology 1998–present.

Representative publications

• Wandersee NJ, Tait JF, Barker JE. Erythroid Phosphatidylserine Exposure is not Predictive of Thrombotic Risk in Mice with Hemolytic Anemia. Blood Cells, Molecules and Diseases. 2000; 26:75-83.
• Wandersee NJ, Birkenmeier CS, Gifford EJ, Mohandas N, Barker JE. Murine Hereditary Spherocytosis, sph/sph, is Caused by a Mutation in the Erythroid a-spectrin Gene. The Hematology Journal. 2000; 1:235-243.
• Wandersee NJ, Roesch AN, Hamblen NR, de Moes J, van der Valk MA, Bronson RT, Gimm JA, Mohandas N, Demant P, Barker JE. Defective Spectrin Integrity and Neonatal Thrombosis in the First Mouse Model for Severe Hereditary Elliptocytosis. Blood. 2001; 97:543-550.
• Wandersee NJ, Lee JC, Deveau SA, Barker, JE. Reduced Incidence of Thrombosis in Mice with Hereditary Spherocytosis Following Neonatal Treatment with Normal Hematopoietic Cells. Blood. 2001; 97:3972-3975.
• Wandersee NJ, Birkenmeier CS, Bodine DM, Mohandas N, Barker JE. Mutations in the Murine Erythroid Alpha-spectrin Gene Alter Spectrin mRNA and Protein Levels and Spectrin Incorporation into the Red Blood Cell Membrane Skeleton. Blood. 2003; 101:325-330.
• Wandersee NJ, Olson SC, Holzhauer SL, Hoffmann RG, Barker JE, Hillery CA. Increased Erythrocyte Adhesion in Mice and Humans with Hereditary Spherocytosis and Hereditary Elliptocytosis. Blood. 2004; 103:710-716.

Grants

• Mechanisms of Vascular Injury in Murine Hemolytic Anemia, American Heart Association, National Center, principal investigator.

Contact
Children's Research Institute
8701 Watertown Plank Road
Wauwatosa, WI 53226
Phone: (414) 937-3815
Fax: (414) 937-6811
E-mail: nancy.wandersee@bcw.edu