Xujing Wang, PhD
 Titles
Investigator, Children's Research Institute; associate professor, Pediatrics, Medical College of Wisconsin.
Division
Endocrinology/Diabetes
Research center/program
Max McGee National Research Center for Juvenile Diabetes
Research interests
Endocrine disorders, genetic diseases/genomics
Research interests
Bioinformatics, genetics of complex diseases, mathematical biology.
Education
Doctorate, Texas A&M University, College Station, 1995.
Honors
China-U.S. Physics Education Association exam winner, 1988; Theodore Law UCF Scientific Achievement Fellowship, 1997.
Representative publications
Wang X, Yang J, Gascoyne PRC. Role of Peroxide in AC Electrical Field Exposure Effects on Friend Murine Erythroleukemia Cells during Dielectrophoretic Manipulations. Biochemistry, Biophysica and Molecular Biology. 1999; Acta 1426(1):53-68.
Yang J, Huang Y, Wang X, Becker FF, Gascoyne PRC. Dielectric Properties of Human Leukocyte Subpopulations Determined by Electrorotation as a Cell Separation Criterion. Biophysical Journal. 1999; 76:3307-3314.
Wang X, Ghosh S, Guo SW. Quantitative Quality Control in Microarray Image Processing and Data Acquisition. Nucleic Acids Research. 2001; 29(15):e75.
Wang X, Becker FF, Gascoyne PRC. Alterations in Membrane Dielectric Responses Precede Surface Expression of PS or DNA-fragmentation in Apoptotic HL-60 Cells. Biochemistry, Biophysics and Molecular Biology. 2002; Acta 1564(2):412-420.
Wang X, Hessner MJ, Wu Y, Pati N, Ghosh S. Quantitative Quality Control in Microarray Experiment and the Application in Data Filtering, Normalization and False Positive Rate Prediction. Bioinformatics. 2003; 19:1341-1347.
Wang X, Jia S, Xiang B, Jiang N, Meyer L, Chen Li Y, Moreno-Quinn C, Ghosh S, Jacob HJ, Hessner MJ. Accurate Gene Expression Measurements by cDNA Microarrays Utilizing TDAV. BMC Bioinformatics. 2006; 7(1):378.
Nittala A, Ghosh S, Stefanovski D, Bergman R, Wang X. Dimensional Analysis of MINMOD Leads to Definition of the Disposition Index and Improved Simulation Algorithm. Biomedical Engineering Online. 2006; 5(44):doi:10.1186/1475-925X-5-44.
Wang X, He Z, Ghosh S. Investigation of the Age-at-onset Heterogeneity in Type 1 Diabetes through Mathematical Modeling. Mathematical Biosciences. 2006; 203(1):79-99.
Nittala A, Ghosh S, Wang X. The Oscillatory Insulin Secretion from Pancreatic Islet Depends on its Architecture. PLoS ONE. 2007; 2(10):e983, doi:10.1371/journal.pone.0000983.
Gao S, Wang X. Topological Analysis of Genetic Networks and Association with Clinical Phenotypes. Bioinformatics. 2007.
Grants
Genetics of Non-HLA Genes in Post-adolescent Onset Type 1 Diabetes Mellitus, co-investigator, Juvenile Diabetes Research Foundation.
High Density Microarrays with Quantitative QC/QA, co-investigator, National Institutes of Health.
Genetic Dissection of a QTL Affecting the Lipid Profile, co-investigator, NIH.
Identifying Drug Toxicity Signatures using QC Arrays, co-investigator, NIH/National Cancer Institute.
Robust T-cell Immunity to Influenza in Human Populations, co-investigator, NIH.
Role of Leptin in Hormone-resistant Prostate Cancer Cell Growth, co-investigator, Medical College of Wisconsin Cancer Center.
Contact
Children's Research Institute
8701 Watertown Plank Road
Wauwatosa, WI 53226
Phone: (414) 456-490
Fax: (414) 456-6663
E-mail: xujing@mcw.edu
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