Xujing Wang, PhD       

Titles
Investigator, Children's Research Institute; associate professor, Pediatrics, Medical College of Wisconsin.

Division
Endocrinology/Diabetes

Research center/program
Max McGee National Research Center for Juvenile Diabetes

Research interests
Endocrine disorders, genetic diseases/genomics

Research interests
Bioinformatics, genetics of complex diseases, mathematical biology.

Education
Doctorate, Texas A&M University, College Station, 1995.

Honors
China-U.S. Physics Education Association exam winner, 1988; Theodore Law UCF Scientific Achievement Fellowship, 1997.

Representative publications

  • Wang X, Yang J, Gascoyne PRC. Role of Peroxide in AC Electrical Field Exposure Effects on Friend Murine Erythroleukemia Cells during Dielectrophoretic Manipulations. Biochemistry, Biophysica and Molecular Biology. 1999; Acta 1426(1):53-68.
  • Yang J, Huang Y, Wang X, Becker FF, Gascoyne PRC. Dielectric Properties of Human Leukocyte Subpopulations Determined by Electrorotation as a Cell Separation Criterion. Biophysical Journal. 1999; 76:3307-3314.
  • Wang X, Ghosh S, Guo SW. Quantitative Quality Control in Microarray Image Processing and Data Acquisition. Nucleic Acids Research. 2001; 29(15):e75.
  • Wang X, Becker FF, Gascoyne PRC. Alterations in Membrane Dielectric Responses Precede Surface Expression of PS or DNA-fragmentation in Apoptotic HL-60 Cells. Biochemistry, Biophysics and Molecular Biology. 2002; Acta 1564(2):412-420.
  • Wang X, Hessner MJ, Wu Y, Pati N, Ghosh S. Quantitative Quality Control in Microarray Experiment and the Application in Data Filtering, Normalization and False Positive Rate Prediction. Bioinformatics. 2003; 19:1341-1347.
  • Wang X, Jia S, Xiang B, Jiang N, Meyer L, Chen Li Y, Moreno-Quinn C, Ghosh S, Jacob HJ, Hessner MJ. Accurate Gene Expression Measurements by cDNA Microarrays Utilizing TDAV. BMC Bioinformatics. 2006; 7(1):378.
  • Nittala A, Ghosh S, Stefanovski D, Bergman R, Wang X. Dimensional Analysis of MINMOD Leads to Definition of the Disposition Index and Improved Simulation Algorithm. Biomedical Engineering Online. 2006; 5(44):doi:10.1186/1475-925X-5-44.
  • Wang X, He Z, Ghosh S. Investigation of the Age-at-onset Heterogeneity in Type 1 Diabetes through Mathematical Modeling. Mathematical Biosciences. 2006; 203(1):79-99.
  • Nittala A, Ghosh S, Wang X. The Oscillatory Insulin Secretion from Pancreatic Islet Depends on its Architecture. PLoS ONE. 2007; 2(10):e983, doi:10.1371/journal.pone.0000983.
  • Gao S, Wang X. Topological Analysis of Genetic Networks and Association with Clinical Phenotypes. Bioinformatics. 2007.

Grants

  • Genetics of Non-HLA Genes in Post-adolescent Onset Type 1 Diabetes Mellitus, co-investigator, Juvenile Diabetes Research Foundation.
  • High Density Microarrays with Quantitative QC/QA, co-investigator, National Institutes of Health.
  • Genetic Dissection of a QTL Affecting the Lipid Profile, co-investigator, NIH.
  • Identifying Drug Toxicity Signatures using QC Arrays, co-investigator, NIH/National Cancer Institute.
  • Robust T-cell Immunity to Influenza in Human Populations, co-investigator, NIH.
  • Role of Leptin in Hormone-resistant Prostate Cancer Cell Growth, co-investigator, Medical College of Wisconsin Cancer Center.

Contact
Children's Research Institute
8701 Watertown Plank Road
Wauwatosa, WI 53226
Phone: (414) 456-490
Fax: (414) 456-6663
E-mail:
xujing@mcw.edu

Investigator in the areas of: