James J. Nocton, MD

James Nocton, MDTitles
Medical director, Medical Education, Children's Hospital of Wisconsin; associate professor, Pediatrics, Medical College of Wisconsin.

Division
Rheumatology

Research interests
Rheumatological disorders

Study interests
Clinical trials, infectious arthritis, systemic lupus erythematosus.

Education
Medical degree, Johns Hopkins University School of Medicine, Baltimore, 1983-1987; residency, Pediatrics, Case Western Reserve University, Cleveland, 1987-1991; fellowship, Rheumatology, Tufts University, Medford, Mass., 1991-1994.

Certifications
Pediatrics, 1990; Pediatric Rheumatology, 1996.

Honors
Top 10 Outstanding Teachers, Department of Pediatrics, as rated by medical students and by residents, 1995–1996; Top 10 Outstanding Teachers, Department of Pediatrics, as rated by medical students, 1996–1997; Preceptor, American College of Rheumatology, Medical Student Clinical Preceptorship, Medical College of Wisconsin (national, competitive application process successfully obtained funding for a medical student to spend eight weeks gaining experience in pediatric rheumatology), 1996; Outstanding Teacher of Residents, Department of Pediatrics, Medical College of Wisconsin (received highest teaching ratings among full-time faculty in the department), 1998, 2000; Arthritis Foundation, Wisconsin Chapter, Outstanding Health Professional Award, (awarded to one outstanding health professional in the state of Wisconsin each year for volunteer service to the Arthritis Foundation and its programs), 1998. Elected to Alpha Omega Alpha, 2008; Preceptor, American College of Rheumatology Medical Student Preceptorship, 2009; elected to the Medical College of Wisconsin Society of Teaching Scholars, 2010; Outstanding Teacher of Medical Students, 2010.

Representative publications                                       

  • Nocton JJ, Steere AC. Lyme Disease. Advances in Internal Medicine. 1995; 40:69-117.
  • Nocton JJ, Bloom BJ, Rutledge BJ, Persing DH, Logigian EL, Schmid CH, Steere AC. Detection of Borrelia Burgdorferi DNA by Polymerase Chain Reaction in Cerebrospinal Fluid in Lyme Neuroborreliosis. Journal of Infectious Disease. 1996; 174:623-7.
  • Lovell DJ, Giannini FH, Reiff A, Cawkwell GD, Silverman ED, Nocton JJ, Stein LD, Gedalia A, Ilowite NT, Wallace CA, Whitmore J, Finck B. Etanercept in Children with Polyarticular Juvenile Rheumatoid Arthritis. New England Journal of Medicine. 2000; 342:763-9.
  • Lewis DA, Nocton JJ. On Call: Pediatrics. Second Edition. Editors: W.B. Saunders, New York, New York, 2001.
  • Chaim JO, Reiff A, Armstrong DL, Myones BL, Silverman E, Klein-Gitelman M, McCurdy D, Wagner-Weiner L, Nocton JJ, Solomon A, Zidovetzki R. Identification of Novel Susceptibility Genes in Childhood-onset Systemic Lupus Erythematosus using a Uniquely Designed Candidate Gene Pathway Platform. Arthritis and Rheumatism. 2007; 56 (12):4164-4173.
  • Namjou B, Stestak AL, Armstrong DL, Zidovetzki R, Kelly JA, Jacob N, Ciobanu V, Kaufman KM, Ojwang JO, Ziegler J, Quismorio F, Reiff A, Myones BL, Guthridge JM, Nath SK, Bruner GR, Mehrian-Shai R, Silverman E, Klein-Gitelman M, Mc Curdy B, Wagner-Weiner L, Nocton JJ, Putterman C, Bae SC, Kim YJ, Petri M, Reveille JD, Vyse TJ, Gilkeson GS, Kamen DL, Alarcon-Riquelme ME, Gaffney PM, Moser KL, Merrill JT, Scofield RH, James JA, Langefeld CD, Harley JB, Jacob CO. High Density Genotyping of STAT4 Gene Reveals Multiple Haplotypic Associations with Systemic Lupus Erythematosus in Different Racial Groups. Arthritis and Rheumatism.  2009; 60 (4):1085-1095.

Grants

  • The Treatment of Juvenile Rheumatoid Arthritis with Gammalinolenic Acid, multicenter clinical trial, subcontract with University of Massachusetts under FDA Grant #FD-R-00106702, principal investigator, Medical College of Wisconsin site, 4/1/96-3/1/97.
  • Health Outcomes in Juvenile Rheumatoid Arthritis, multicenter study, American Academy of Pediatrics, principal investigator, Medical College of Wisconsin site, 1997-1999.
  • Open-label Extension Treatment with TNFR: Fc for Participating Patients in TNFR: Fc Clinical Trials, multicenter study, Immunex Corporation, principal investigator, Medical College of Wisconsin site, 1998-2006.
  • Phase IV Registry of Etanercept (Enbrel) in Children with Juvenile Rheumatoid Arthritis, multicenter study, Immunex Corporation, co-investigator, Medical College of Wisconsin site, 2001-2005.
  • Double-blind Randomized Placebo-controlled Study Comparing Meloxicam and Naproxen in Children with Juvenile Rheumatoid Arthritis, Boehringer-Ingelheim, principle investigator, 9/15/01–9/15/04.
  • Genetics of Pediatric-onset Systemic Lupus Erythematosus, National Institutes of Health IR01 AR45650, subcontract #H15990, subcontract from Children's Memorial Hospital, Chicago, subcontract awarded to James J. Nocton, MD, 8/2000–12/2005.

Contact
Children's Research Institute
8701 Watertown Plank Road
Wauwatosa, WI 53226
Phone: (414) 266-6700
Fax: (414) 266-6695
E-mail address: jnocton@mcw.edu 

Investigator in the areas of: