Sandra L. Haberichter, PhD      

Titles
Investigator, Children's Research Institute; assistant professor, Medical College of Wisconsin.

Division
Hematology, Oncology and Transplant

Research interests
Bleeding and blood disorders

Study interests
Mechanisms of regulated storage and secretion in endothelial cells and platelets, molecular mechanisms of von Willebrand disease.

Education
Doctorate, University of Wisconsin-Milwaukee, 1998; fellowship, Blood Research Institute, BloodCenter of Wisconsin, Milwaukee, 1998-2003.

Representative publications

• Haberichter SL, Jacobi P, Montgomery RR. Critical Independent Regions in the VWF Propeptide and Mature VWF that Enable Normal VWF Storage. Blood. 2003; 101:1384-1391.
• Wilcox DA, Shi Q, Nurden P, Haberichter SL, Rosenberg JB, Johnson BD, Nurden AT, White II GC, Montgomery RR. Induction of Megakaryocytes to Synthesize and Store a Releasable Pool of Human Factor VIII. Journal of Thrombosis and Haemostasis l. 2003; 2477-2489.
• Haberichter SL, Merricks EP, Fahs S, Christopherson P, Nichols TC, Montgomery RR. Re-establishment of VWF-Dependent Weibel-Palade Bodies in VWD Endothelial Cells. Blood. 2005; 105:145-152.
• Haberichter SL, Shi Q,  Montgomery RR. The Regulated Release of VWF and FVIII and the Biologic Implications. Pediatric Blood and Cancer. 2006; 46:547-553.
• Michaux G, Abbitt KB, Collinson LM, Haberichter SL, Norman KE, Cutler DF. The Unique Shape of Endothelial Weibel-Palade Bodies is Necessary for the Physiological Function of von Willebrand Factor. Molecular Cell. 2006; 10:223-232.
• Michaux G, Pullen TJ, Haberichter SL, Cutler DF. P-Selectin Binds to the D'-D3 Domains of von Willebrand Factor in Weibel-Palade Bodies. Blood. 2006; 107:3922-3924.
• Haberichter SL, Gavazova S, Gill JC, Buccholz NP, Fahs SF, Christopherson PA, Friedman KD, Montgomery RR. Assay of the von Willebrand Factor Propeptide to Identify VWD Patients with Decreased VWF Survival Phenotype. Blood. 2006.

Grants

• The Role of von Willebrand Factor in Weibel-Palade body Formation in Canine Endothelium, American Heart Association National Scientist Development Grant, principal investigator.
• Program Project Grant: Molecular and Clinical Biology of VWD, project 2-Molecular Mechanisms of VWF Alteration in Vitro/vivo, PO1-HL081588-01, principal investigator.

Contact
Children's Research Institute
8701 Watertown Plank Road
Wauwatosa, WI 53226
Phone: (414) 456-7631
Fax: (414) 456-6328
E-mail: shaberic@mcw.edu