Sandra L. Haberichter, PhD      

Titles
Investigator, Children's Research Institute; associate professor, Medical College of Wisconsin.

Division
Hematology, Oncology and Transplant

Research center/program
Bleeding Disorders research

Research interests
Bleeding and blood disorders, cell and developmental biology

Study interests
von Willebrand disease, von Willebrand factor, endothelial cells, protein trafficking, mouse models.

Education
Doctorate, University of Wisconsin-Milwaukee, 1998; fellowship, Blood Research Institute, Blood Center of Wisconsin, Milwaukee, 1998-2003.

Honors
Young Investigator Award International Society for Thrombosis and Haemostasis; Symposium HOT Topic Presenter, International Society for Thrombosis and Haemostasis; member: American Society of Hematology; International Society on Thrombosis and Haemostasis, American Heart Association - Scientific Council; Ad hoc reviewer for Blood, Journal of Thrombosis and Haemostasis, Thrombosis and Haemostasis, Arteriosclerosis, Thrombosis and Vascular Biology; Ad hoc reviewer, NIH Study Section for Hemostasis and Thrombosis.

Representative publications

• Michaux G, Abbitt KB, Collinson LM, Haberichter SL, Norman KE, Cutler DF. The Unique Shape of Endothelial Weibel-Palade Bodies is Necessary for the Physiological Function of von Willebrand Factor. Developmental Cell. 2006; 10:223-232.
• Haberichter SL, Balistreri M, Christopherson P, Morateck P, Gavazova S, Bellissimo DB, Manco-Johnson MJ, Gill JC, Montgomery RR. Assay of the von Willebrand factor (VWF) Propeptide to Identify Patients with Type 1 von Willebrand Disease VWD with Decreased VWF Survival. Blood. 2006. 108:3344-3351.
• Maroney SA, Haberichter SL, Friese P, Paul M, Ferrel JP, Dale G, Mast AE. Active Tissue Factor Pathway Inhibitor is Expressed on the Surface of Coated Platelets. Blood. 2007. 109:1931-1937.
• Haberichter SL, Castaman G, Peake I, Goodeve A, Rodeghiero F, Federici A, Batlle J, Meyer, D, Mazurier C, Goudemand J, Eikenboom J, Schneppenheim R, Budde U, Ingerslev J, Vorlova Z, Habart D, Holmberg L, Lethagen S, Pasi J, Hill F, Montgomery RR. Identification of Type 1 von Willebrand Disease Patients with Reduced von Willebrand Factor Survival by Assay of the VWF Propeptide in the European Study: Molecular and Clinical Markers for the Diagnosis and Management of Type 1 VWD (MCMDM-1 VWD). Blood. 2008. 111:4979-4985.
• Haberichter SL, Allmann AM, Jozwiak MA, Montgomery RR, Gill JC. Genetic Alteration of the D2 Domain Abolishes von Willebrand Factor Multimerization and Trafficking to Storage. Journal of Thrombosis and Haemostasis. 2009. 7, 641-50.
• Haberichter SL. VWF and FVIII - The Origins of a Great Friendship. Blood. 2009. 113, 2873-74.

Grants

• "Molecular Mechanisms of VWF Alteration in Vitro and Vivo", National Institutes of Health/NHLBI, principal investigator.

Contact
Children's Research Institute
8701 Watertown Plank Road
Wauwatosa, WI 53226
Phone: (414) 456-7631
Fax: (414) 456-6328
E-mail: shaberic@mcw.edu