Calvin B. Williams, MD, PhD
 Titles
D.B. and Marjorie Reinhart Chair in Rheumatology, Children's Hospital of Wisconsin; associate professor, Pediatrics (Microbiology and Molecular Genetics), section chief, Pediatric Rheumatology, Medical College of Wisconsin.
Division
Asthma, Allergy and Immunology, Rheumatology
Research center/program
Jeffrey Modell Diagnostic Center for Primary Immunodeficiencies
Research interests
Rheumatological disorders, infectious/immunological diseases
Study interests
Autoimmunity, regulatory T-cell biology, T-cell development.
Education
Medical degree, University of California, Irvine, 1991; doctorate, University of California, Irvine, 1991; residency, St. Louis Children's Hospital, 1993, fellowship, Washington University School of Medicine and St. Louis Children's Hospital, 1996.
Certifications
Pediatrics, Pediatric Rheumatology.
Honors
Summer fellowship, California Foundation for Biochemical Research, 1982; Earl C. Anthony Dissertation Fellowship, 1989; MRES Medical Scientist Student Scholarship, 1990; Vincent P. Carroll Jr. Memorial Research Award for Outstanding Research, 1992; Scholar of the Center for Child Health Research at Washington University, 1997; Basil O'Connor Research Award, March of Dimes, 1998; D.B. and Marjorie Reinhart Chair in Rheumatology, 2002; Elected member, Society for Pediatric Research, 2003; Outstanding Health Professional Award-Arthritis Foundation, Wisconsin Chapter, 2004.
Representative publications
Haribhai D, Meyer MM, Engle DL, White JM, Williams CB. A Threshold for T-cell Tolerance to an Inducible Serum Protein. Journal of Immunology. 2003; 170:3007-14.
Singh J, Williams CB, McAlister WH. Talo-patello-scaphoid Osteolysis, Synovitis and Short Fourth Metacarpals in Sisters: A New Syndrome? American Journal of Medical Genetics. 2003; 121A(2):118-125.
Harbhai D, Edwards B, Williams ML, Williams CB. Functional Reprogramming of the Primary Immune Response by T-cell Receptor Antagonism. Journal of Experimental Medicine. 2004; 200:1371-82.
Lin D, Truong N, Grossman WJ, Haribhai D, Williams CB, Wang J, Martin MG, Chatila TA. Allergic Dysregulation and Hyperimmunoglobulinemia E in Foxp3 Mutant Mice. Journal of Allergy and Clinical Immunology. 2005; 116:1106-15.
Haribhai D., Lin W, Relland LM, Truong N, *Chatila TA, *Williams CB. Regulatory T-cells Dynamically Control the Primary Immune Response to Foreign Antigen. Journal of Immunology. 2007; 178:2961-72. *Denotes shared corresponding authorship.
Lin W, Haribhai D, Relland LM, Truong N, Carlson MR, *Williams CB, *Chatila TA. Regulatory T-cell Development in the Absence of a Functional Foxp3 Protein. National Immunology. 2007; 8:359-68. *Denotes shared corresponding authorship.
Grants
Immune Function and Biodefense in Children, Elderly and Immunocompromised Populations, co-investigators, National Institutes of Health, National Institute of Allergy and Infectious Diseases.
The Role of Induced Regulatory T-cells in Dominant Immunological Tolerance, principal investigator, Advancing a Healthier Wisconsin.
Contact
Children's Research Institute
8701 Watertown Plank Road
Wauwatosa, WI 53226
Phone: (414) 456-4343
Fax: (414) 266-6695
E-mail: cwilliam@mcw.edu
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