Cheryl A. Hillery, MD

Hematology and Oncology

Title(s): Assistant professor, Pediatrics (Hematology/Oncology), Medical College of Wisconsin.

Education: Medical degree, Duke University School of Medicine, Durham, N.C., 1984; residency, Internal Medicine and Pediatrics, University of North Carolina Hospitals, Chapel Hill, 1988; fellowship: Hematology/Oncology, departments of Pediatrics and Medicine, University of North Carolina, Chapel Hill, 1991; postdoctoral fellowship, Hematology, Blood Research Institute, Blood Center of Southeastern Wisconsin, Milwaukee, Wis., 1993.

Certification(s): Internal Medicine, 1988; Pediatrics, 1989 and 2000; Pediatric Hematology and Oncology, 1992 and 2000.

Honors: NIH Career Development Award (K08/CIDA), 1993–1998; Society of Pediatric Research, 1996.

Research interests: Vasopathology of sickle cell disease.

Representative Publications:

• Watkins NA, Du LM, Scott JP, Ouwehand WH, Hillery CA. Single Chain Antibody Fragments Derived from a Human Synthetic Phage Display Library Bind Thrombospondin and Inhibit Sickle Cell Adhesion. Blood 102:718-724.
• Ou J, Ou Z, Jones DW, Holzhauer S, Hatoum OA, Ackerman AW, Weihrauch DW,  Gutterman DD, Guice K, Oldham KT, Hillery CA,* Pritchard, Jr KA*. L-4F, an Apo A-1 Mimetic, Dramatically Improves Vasodilation in Hypercholesterolemia and Sickle Cell Disease. Circulation 107:2337-41. *Contributed equally to experimental design.
• Saunthararajah Y, Hillery CA, Lavelle D, Molokie R, Dorn L, Bressler L, Gavazova S, Chen YH, Hoffman R, DeSimone J. Effects of 5-aza-2'-deoxycytidine on Fetal Hemoglobin Levels, Red-Cell Adhesion and Hematopoietic Differentiation in Patients with Sickle Cell Disease. Blood 102:3865-70 (plenary paper).
• Wandersee NJ, Olson SC, Holhzaur SL, Hoffmann RG, Barker JE, Hillery CA. Increased Erythrocyte Adhesion in Mice and Humans with Hereditary Spherocytosis and Hereditary Elliptocytosis. Blood 103:710-6.
• Pritchard, Jr. KA, Ou J, Ou Z, Shi Y, Franciosi JP, Signorino P, Kaul S, Ackland-Burglund C, Witte K, Holzhauer S, Mohandas N, Guice K, Oldham KT, Hillery CA. Hypoxia-Induced Acute Lung Injury in Murine Models of Sickle Cell Disease. American Journal of Physiology: Lung Cellular Molecular Physiology 286:L705-L714 (with editorial comment and cover photo).
• Hillery CA, Panepinto JA. Pathophysiology of Stroke in Sickle Cell Disease. Microcirculation 11: 195-208.

Current grants:

• Mechanisms of Vaso-Occlusion in Sickle Cell Disease: Role of Thrombosis, NIH program project: Project 4, PI.
• Red Blood Cell Adhesion in Sickle Cell Disease, NIH R01, PI.          

Contact information: PO Box 2176, Milwaukee, WI 53201-2178. Phone: (414) 937-3896. Fax: (414) 937-6811. E-mail: chillery@bcw.edu.