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David Bick, MD

Genetics

David Bick, MDTitle(s): Associate professor, Medical College of Wisconsin.

Education: Medical degree, George Washington University School of Medicine, Washington, D.C., 1977-1981; residency, Yale New Haven Hospital, New Haven, Conn., 1981-1984; fellowship, Yale School of Medicine, New Haven, Conn., 1984-1986.

Certification(s): American Board of Pediatrics, American Board of Clinical Genetics.

Honors: NNational Foundation March of Dimes Summer Science Research Grant Program for Medical Students, 1978; Alpha Omega Alpha Medical Honor Society, 1981; University of Texas Health Science Center At San Antonio Institutional Research Grant: "Physical mapping of the X-linked Kallmann syndrome locus," 1988; Institute of Research and Education INOVA Health System: "Molecular analysis of colorectal cancer susceptibility gene in patients with colorectal polyps and cancer," 1993.

Research interests: Preimplantation genetic diagnosis, genes causing mental retardation and learning disabilities.

Representative publications:

  • Achermann JC, Gu W-X, Kotlar TJ, Meeks JJ, Sabacan LP, Seminara SB, Habiby RL, Hindmarsh PC, Bick DP, Sherins RJ, Crowley Jr. WF, Layman LC, Jameson JL. Mutational Analysis of DAX1 in Patients with Hypogonadotropic Hypogonadism or Pubertal Delay. Journal of Clinical Endocrinology and Metabolism 84:4497-4500, 1999.
  • Bhagavath B, Ozata M, Ozdemir IC, Bolu E, Bick DP, Sherins RJ, Layman LC. The Prevalence of Gonadotropin-Releasing Hormone Receptor Mutations in a Large Cohort of Patients with Hypogonadotropic Hypogonadism. Fertility and Sterility 2005 Oct;84(4):951-7. PMID: 16213849 [PubMed - indexed for MEDLINE].
  • Bhagavath B, Podolsky RH, Ozata M, Bolu E, Bick DP, Kulharya A, Sherins RJ, Layman LC. Clinical and Molecular Characterization of a Large Sample of Patients with Hypogonadotropic Hypogonadism. Fertility and Sterility 2006 Mar;85(3):706-13. PMID: 16500342 [PubMed - indexed for MEDLINE].
  • Bhagavath B, Xu N, Ozata M, Rosenfield RL, Bick DP, Sherins RJ, Layman LC. KAL1 Mutations are not a Common Cause of Idiopathic Hypogonadotrophic Hypogonadism in Humans. Molecular Human Reproduction 2007 Mar;13(3):25-30. Epub 2007 Jan 9. PMID: 17213338 [PubMed - in process].
  • Bick DP, Fugger EF, Pool S, Hazelrigg WB, Yadvish KN, Spence WC, Maddalena A, Howard-Peebles PN, Schulman JD. Semen Donor Screening for Hereditary Diseases: The Fairfax Cryobank Experience. Journal of Reproductive Medicine 43:423-428, 1998.
  • Bick DP, Lau EC. Preimplantation Genetic Diagnosis. Pediatric Clinics of North America 2006 Aug;53(4):559-77. Review. PMID: 16872993 [PubMed - indexed for MEDLINE].
  • Bick DB, McCorkle D, Stanley WS, Stern HJ, Staszak P, Berkovitz GD, Meyers CM, Kelley RI. Short Communication: Prenatal Diagnosis of Smith-Lemli-Opitz Syndrome in a Pregnancy with Low Maternal Serum Oestriol and a Sex-Reversed Fetus. Prenatal Diagnosis 19:68-71, 1999.
  • Fallon L, Harton GL, Sisson ME, Rodriguez E, Field LK, Fugger EF, Geltinger M, Sun Y, Dorfmann A, Schoener C, Bick D, Schulman J. Preimplantation Genetic Diagnosis for Spinal Muscular Atrophy Type I. Neurology 53:1087-1090, 1999.
  • Johnston JJ, Walker RL, Davis S, Facio F, Turner JT, Bick DP, Daentl DL, Ellison JW, Meltzer PS, Biesecker LG. Zoom-in Comparative Genomic Hybridisation Arrays for the Characterisation of Variable Breakpoint Contiguous Gene Syndromes. Journal of Medical Genetics 2007 Jan;44(1):e59. Epub 2006 Nov 10. PMID: 17098889 [PubMed - indexed for MEDLINE].
  • Klein OD, Cotter PD, Schmidt AM, Bick DP, Tidyman WE, Albertson DG, Pinkel D, Rauen KA. Interstitial Deletion of Chromosome 12q: Genotype-Phenotype Correlation of Two Patients Utilizing Array Comparative Genomic Hybridization. American Journal of Medical Genetics 2005 Nov 1;138(4):349-54. PMID: 16200635 [PubMed - indexed for MEDLINE].
  • Park JK, Ozata M, Chorich LP, Cheng L, Bick DP, Sherins RJ, Ozdemir IC, Bolu E, Cogan JD, Phillips JA, Layman LC. Analysis of the PROP1 Gene in a Large Cohort of Patients with Idiopathic Hypogonadotropic Hypogonadism. Clinical Endocrinology (Oxf). 2004 Jan;60(1):147-9. No abstract available. PMID: 14678304 [PubMed - indexed for MEDLINE].
  • Stavropoulos DJ, Bick D, Kalousek DK. Molecular Cytogenetic Detection of Confined Gonadal Mosaicism in a Conceptus with Trisomy 16 Placental Mosaicism. American Journal of Human Genetics 63:1912-1914, 1998.
  • Taylor HS, Block K, Bick DP, Sherins RJ, Layman LC. Mutation Analysis of the EMX2 Gene in Kallmann's Syndrome. Fertility and Sterility 72:910-914, 1999.

Contact information: Genetics Center, 8701 Watertown Plank Road, Milwaukee, WI 53226. Phone: (414) 266-2979. Fax: (414) 266-1616. E-mail address: dbick@mcw.edu.