Cataracts - a clouding or opaque area over the lens of the eye -- an area that is normally transparent.

Cleft lip and/or cleft palate - congenital birth abnormalities that affect one in every 800 babies. The abnormalities occur in early pregnancy, when the left and right sides of the lip and roof of the mouth normally fuse together. Cleft lip is a separation in the upper lip. Cleft palate is a separation in the roof of the mouth.

Congenital heart disease - a condition in which the heart or blood vessels near the heart do not develop normally before birth.

Contractures - stiff joints.

Diaphragmatic hernia - a birth defect in which an opening is present in the diaphragm (the muscle that separates the chest cavity from the abdominal cavity). With this type of birth defect, some of the organs that are normally found in the abdomen move up into the chest cavity through this abnormal opening.

Genital malformations - malformations of either the female or male genitals (sex organs).

Glaucoma - increased intra-ocular pressure in the eye that can result in optic nerve damage and loss of sight.

Misshapen skull

Missing fingers or toes

Missing or incomplete arms/legs

Spina bifida or open spine defects - neural tube defects in which the neural tube fails to close somewhere along the spine.

Other problems present at birth

Bleeding disorders

Childhood cancers

Kidney or urinary tract disease

Slow growth or short stature

Cystic fibrosis - an inherited autosomal recessive condition that causes the secretion of abnormal mucus in the lungs and problems with pancreas function and food absorption.

Sickle cell disease - an inherited autosomal recessive condition that causes abnormal hemoglobin in blood cells, leading to infections and organ damage.

Thalassemia

Other chronic disease

Autism

Attention deficit/hyperactivity - a group of symptoms or signs that is usually characterized by serious and persistent difficulties resulting in inattentiveness or "distractibility", impulsivity, and hyperactivity.

Developmental delay

Failure to thrive

Learning disability - a disorder that affects people's ability to either interpret what they see and hear or to link information from different parts of the brain. These limitations can show up in many ways -- as specific difficulties with spoken and written language, coordination, self-control, or attention. Such difficulties extend to schoolwork and can impede learning to read or write, or to do math.

Loss of developmental skills

Low muscle tone

Mental illness

Mental retardation

Speech problems

Seizures

Extreme farsightedness - also known as hyperopia, farsightedness is the most common refractive error in which an image of a distant object becomes focused behind the retina, either because the eyeball axis is too short, or because the refractive power of the object is too weak. This condition makes close objects appear out of focus and may cause headaches and/or eye strain.

Extreme nearsightedness - also known as myopia, nearsightedness is a condition in which, opposite of hyperopia, an image of a distant object becomes focused in front the retina, either because the eyeball axis is too long, or because the refractive power of the object is too strong. This condition makes distant objects appear out of focus and may cause headaches and/or eye strain.

Hearing loss

Retinal or other visual problems

Ear abnormalities

Unusually shaped eyes

Different colored eyes

Facial features which are unusual or are very different from other family members

Brittle or sparse hair

Excessive body hair

White patch(es) of hair

Large or small tongue

Misshapen teeth

Missing or extra teeth

Loose or stiff joints

Unusually tall or short stature

Webbing between fingers or toes

Excessive skin

Unusual birthmarks

Increased or decreased sweating

Unusual body odor

Any other unusual features